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Matrix Metalloproteinase 24 (MMP24) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2027035
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MBS2027035 is an antibody targeting MMP24. Also known as Polyclonal Antibody to Matrix Metalloproteinase 24 (MMP24). Reactive in Human, Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Matrix Metalloproteinase 24 (MMP24), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Matrix Metalloproteinase 24 (MMP24)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- ID AAYERADGRF VFFKGDKYWV FKEVTVEPGY PHSLGELGSC LPREGIDTAL RWEPVGKTYF FKGERYWRYS EERRATDPGY PKPITVWKGI PQAPQGAFIS KEGYYTYFYK GRDYWKFDNQ KLSVEPGYPR NILRDWMGCN QKEVERRKER RLPQDDVDIM VTINDVPGSV NAVAVVIPCI LSLCILVLVY
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against MMP24. It has beenselected for its ability to recognize MMP24 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: MMP24 (MBS2027035)
Immunogen: MMP24 (MBS2031459)
Matching Pairs
Unconjugated Antibody: MMP24 (MBS2027035)
APC-CY7 Conjugated Antibody: MMP24 (MBS2060368)
Molecular Weight
73,231 Da
OMIM
AF131284 mRNA
3D Structure
ModBase 3D Structure for Q9Y5R2
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
MMP24 (Ile429~Gln642)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human, Rat
Conjugate
No Conjugate
Immunogen
Recombinant MMP24 (Ile429~Gln642) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2060370
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MMP24 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-MMP24 antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-MMP24 antibody

Western Blot: Sample: Rat Pancreas lysate; Primary Ab: 1.5ug/ml Rabbit Anti-Human MMP24 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-MMP24 Polyclonal Antibody – Cat# MBS2027035

Western Blot (WB) of anti-MMP24 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-MMP24 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2027035

Immunohistochemistry (IHC) of anti-MMP24 antibody

DAB staining on fromalin fixed paraffin-embedded Kidney tissue)
Rabbit Anti-MMP24 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027035

Immunohistochemistry (IHC) of anti-MMP24 antibody

DAB staining on IHC-P; Samples: Human Kidney Tissue)
Rabbit Anti-MMP24 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027035

Other Notes

Small volumes of anti-MMP24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MMP24. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
matrix metalloproteinase-24 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 24
NCBI Official Symbol
MMP24
NCBI Official Synonym Symbols
MMP25; MMP-24; MT5MMP; MTMMP5; MT-MMP5; MT5-MMP; MT-MMP 5
UniProt Protein Name
Matrix metalloproteinase-24
UniProt Synonym Protein Names
Membrane-type matrix metalloproteinase 5; MT-MMP 5; MTMMP5
UniProt Gene Name
MMP24
UniProt Synonym Gene Names
MT5MMP; MMP-24; MT-MMP 5; MTMMP5; MT5-MMP; MT5MMP
NCBI Protein Information
matrix metalloproteinase-24

NCBI Summary for MMP24

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase). [provided by RefSeq, Feb 2016]
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UniProt Comments for MMP24

MMP24: Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin. Belongs to the peptidase M10A family.

Protein type: Activator; EC 3.4.24.-; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: integral component of plasma membrane; proteinaceous extracellular matrix; trans-Golgi network membrane

Molecular Function: cadherin binding; enzyme activator activity; metalloendopeptidase activity; zinc ion binding

Biological Process: detection of temperature stimulus involved in sensory perception of pain; glial cell differentiation; positive regulation of catalytic activity; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MMP24 antibody

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