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BMP and Activin Membrane Bound Inhibitor Homolog (BAMBI) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2027383
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2027383 is an antibody targeting BAMBI. Also known as Polyclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against BAMBI. It has beenselected for its ability to recognize BAMBI in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: BAMBI (MBS2027383)
Immunogen: BAMBI (MBS2030508)
Matching Pairs
Unconjugated Antibody: BAMBI (MBS2027383)
APC-CY7 Conjugated Antibody: BAMBI (MBS2081468)
Molecular Weight
29,108 Da
OMIM
U23070 mRNA
3D Structure
ModBase 3D Structure for Q13145
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
BAMBI (Arg29~Asp130)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant BAMBI (Arg29~Asp130) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2081470
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-BAMBI antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-BAMBI antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-BAMBI antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-BAMBI Polyclonal Antibody – Cat# MBS2027383

Immunohistochemistry (IHC) of anti-BAMBI antibody

DABstainingonIHC-P.Samples:HumanTissue)
Rabbit Anti-BAMBI Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027383

Other Notes

Small volumes of anti-BAMBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BAMBI. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
BMP and activin membrane-bound inhibitor homolog
NCBI Official Synonym Full Names
BMP and activin membrane bound inhibitor
NCBI Official Symbol
BAMBI
NCBI Official Synonym Symbols
NMA
UniProt Protein Name
BMP and activin membrane-bound inhibitor homolog
UniProt Synonym Protein Names
Non-metastatic gene A protein; Putative transmembrane protein NMA
UniProt Gene Name
BAMBI
UniProt Synonym Gene Names
NMA
NCBI Protein Information
BMP and activin membrane-bound inhibitor homolog

NCBI Summary for BAMBI

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]
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UniProt Comments for BAMBI

BAMBI: Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.

Protein type: Inhibitor; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10p12.1

Cellular Component: cytoplasm; integral component of membrane; plasma membrane

Molecular Function: frizzled binding; type II transforming growth factor beta receptor binding

Biological Process: cell migration; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of protein binding; positive regulation of transcription, DNA-templated; regulation of cell shape; transforming growth factor beta receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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