GAGA-POZ Recombinant Protein – Cat# MBS203061

GAGA-POZ Domain (GAGA-POZ) Recombinant Protein

Name: GAGA-POZ Recombinant Protein; GAGA-POZ Domain; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203061
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203061

The GAGA factor is a sequence-specific DNA-binding protein, which participates in the regulation of the expression of a variety of different classes of genes in Drosophila such as many developmentally regulated genes, stress induced genes, and cell cycle… More details

$210 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GAGA-POZ domain, Recombinant Protein

Full Product Name

GAGA-POZ domain, 1-130aa, Drosophila melanogaster, E Coli

Product Gene Name

GAGA-POZ recombinant protein

Product Synonym Names

Trithorax-like isoform A; Trl; Adf-2; GAGA; Nc70F; TFGAGA; GAGA-POZ domain; Trithorax-like protein; GAGA factor; GAF; Adh transcription factor 2; Neural conserved at 70F; Transcription factor GAGA; Trithorax-like isoform A; Trithorax like protein

Sequence

MSLPMNSLYS LTWGDYGTSL VSAIQLLRCH GDLVDCTLAA GGRSFPAHKI VLCAASPFLL DLLKNTPCKH PVVMLAGVNA NDLEALLEFV YRGEVSVDHA QLPSLLQAAQ CLNIQGLAPQ TVTKDDYTTH

Host

E Coli

Form/Format

Liquid. In 10 mM HEPES (pH 7.4), 25mM NaCl

Purity/Purification

> 95% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

14 kDa (130 aa), confirmed by MALDI-TOF.

3D Structure

ModBase 3D Structure for Q08605

Antigen Species

Human

Product Categories/Family for GAGA-POZ recombinant protein

Cell Cycle

Applications Tested/Suitable for GAGA-POZ recombinant protein

SDS-PAGE

Product References and Citations for GAGA-POZ recombinant protein

Kosoy A., et al. (2002) J Biol.Chem. 277 (44), 42280-8.; Espinas ML., et al. (1999) J Biol. Chem. 274 (23),16461-9.; Farkas G., et al. (1994) Nature 371, 806-808.;

Other Notes

Small volumes of GAGA-POZ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAGA-POZ purchase

MBS203061 is a recombinant protein targeting GAGA-POZ. Also known as GAGA-POZ domain, 1-130aa, Drosophila melanogaster, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GAGA-POZ. It may not necessarily be applicable to this product.

NCBI GI #

45553105

NCBI GeneID

2768981

NCBI Accession #

NP_996080

UniProt Primary Accession #

Q08605

UniProt Secondary Accession #

O18349; O18350; O18526; Q08083; Q7JN57; Q8MYL3; Q8T387; Q9V3X7; Q9VUH2

GenBank Nucleotide #

NM_206358.4

NCBI Official Full Name

Trithorax-like, isoform A

NCBI Official Synonym Full Names

Trithorax-like

NCBI Official Symbol

Trl

NCBI Official Synonym Symbols

Adf-2; Adf-2-519; Adf2; anon-EST:fe2E12; CG33261; CG9343; DmelCG33261; E(var)3-trl; E(var)62; Gaf; GAF; gaga; Gaga; GAGA; GAGA factor; l(3)s2325; Nc70F; NC70F; TfGAGA/Adf-2; trl; TRL; Trl-GAGA

UniProt Protein Name

Transcription factor GAGA

UniProt Synonym Protein Names

Adh transcription factor 2; GAGA factor; GAF; Neural conserved at 70F; Trithorax-like protein

UniProt Gene Name

Trl

UniProt Synonym Gene Names

Adf-2; GAGA; Nc70F; TFGAGA; GAF

NCBI Protein Information

CG33261 gene product from transcript CG33261-RI

UniProt Comments for GAGA-POZ

Transcriptional activator that functions by regulating chromatin structure. Overcomes the repressive effects of chromatin by promoting the open chromatin conformation in promoter gene regions, thereby allowing access to other transcription factors. Binds to DNA Polycomb response elements (PREs) at the bithorax complex and to the proximal region of the engrailed promoter, and positively regulates transcription of many genes including homeotic ones. Binds to the DNA sequence (GA)n, with optimal binding to the pentamer 5'-GAGAG-3'. Binds DNA as an oligomer. May also act as a transcriptional repressor, maintaining the repressed state of genes including lolal, and down-regulating its own transcription. Required for dosage compensation in males and may be involved in oogenesis. Also has a role in nuclear division.

Research Articles on GAGA-POZ

1. GAF (Vfl) as an additional factor in regulation of early developmental genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with GAGA-POZ recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>434 publications with GAGA-POZ and Blood
Head Antibodies	>21 publications with GAGA-POZ and Head
Embryonic Tissue Antibodies	>15 publications with GAGA-POZ and Embryonic Tissue
Gonad Antibodies	>12 publications with GAGA-POZ and Gonad
Whole Body Antibodies	>11 publications with GAGA-POZ and Whole Body
Ovary Antibodies	>10 publications with GAGA-POZ and Ovary
Uncharacterized Tissue Antibodies	>2 publications with GAGA-POZ and Uncharacterized Tissue