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Recoverin (RCVRN) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203104

Recoverin is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Recoverin (RCVRN), Recombinant Protein
Full Product Name
Recoverin, 1-200 aa, Human, E Coli
Product Gene Name
Product Synonym Names
RCVRN; RCV1; Recoverin; Cancer-associated retinopathy protein; Protein CAR; Recoverin; Cancer associated retinopathy protein; Cancer associated retinopathy protein antibody; CAR protein
Sequence
MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKN EVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA
Host
E Coli
Form/Format
Liquid. In 20 mM Tris pH 8.0, 1 mM EDTA, 2mM MgCl2, 10% glycerol
Purity/Purification
> 95% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 2 to 8 degree C for 1 week. For long term storage, aliquot and store at -20 to -80 degree C. Avoid repeated freezing and thawing.
Molecular Weight
23 kDa (200 aa), confirmed by MALDI-TOF.
OMIM
S43855 mRNA
3D Structure
ModBase 3D Structure for P35243
Domain
1-200aa
Tag
Non-tagged

Product Categories/Family for RCVRN recombinant protein

Applications Tested/Suitable for RCVRN recombinant protein
SDS-PAGE

SDS-PAGE of RCVRN recombinant protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
RCVRN Recombinant Protein – Cat# MBS203104

Product References and Citations for RCVRN recombinant protein

Sampath P., et al. (2004) Cancer Control. 11, 174-80. Erickson MA., et al. (1998) Proc. Natl. Acad. Sci. 95, 6474-9.

Other Notes

Small volumes of RCVRN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RCVRN purchase

MBS203104 is a recombinant protein targeting RCVRN. Also known as Recoverin, 1-200 aa, Human, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RCVRN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
recoverin
NCBI Official Synonym Full Names
recoverin
NCBI Official Symbol
RCVRN
NCBI Official Synonym Symbols
RCV1
UniProt Protein Name
Recoverin
UniProt Synonym Protein Names
Cancer-associated retinopathy protein; Protein CAR
Protein Family
UniProt Gene Name
RCVRN
UniProt Synonym Gene Names
RCV1; Protein CAR
NCBI Protein Information
recoverin

NCBI Summary for RCVRN

This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]
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UniProt Comments for RCVRN

Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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