GM-CSF Active Protein

Name: GM-CSF Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203121
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203121

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells,… More details

$250 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GM-CSF, Active Protein

Full Product Name

GM-CSF, 18-141aa, Mouse, E Coli (Bioactivity Validated)

Product Gene Name

GM-CSF active protein

Product Synonym Names

Granulocyte-macrophage colony stimulating factor 2; Csf2; Csfgm; MGI-IGM; mGM-CSF; Granulocyte-macrophage colony stimulating factor 2; Granulocyte-macrophage colony stimulating factor 2

Sequence

MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

Host

E Coli

Form/Format

Liquid In phosphate-buffered saline (PBS), pH 7.4, 10% glycerol

Purity/Purification

> 95% by SDS-PAGE

Concentration

1 mg/ml (determined by BCA assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

14 kDa (125 aa), confirmed by MALDI-TOF.

3D Structure

ModBase 3D Structure for P01587

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Antigen Species

Mouse

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Biological Activity

Measured in a cell proliferation assay using MC/9 cells. The ED50 for this effect is less or equal to 0.5 ng/ml.

Product Categories/Family for GM-CSF active protein

Hormones & Cytokines

Applications Tested/Suitable for GM-CSF active protein

SDS-PAGE

Product References and Citations for GM-CSF active protein

Fleetwood AJ., et al, (2005). Crit Rev Immunol. 25 (5):405-28.; Hamilton JA., et al. (2004). Growth Factors. 22 (4):225-31.;

Other Notes

Small volumes of GM-CSF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GM-CSF purchase

MBS203121 is an active protein targeting GM-CSF. Also known as GM-CSF, 18-141aa, Mouse, E Coli (Bioactivity Validated). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GM-CSF. It may not necessarily be applicable to this product.

NCBI GI #

110625658

NCBI GeneID

12981

NCBI Accession #

NP_034099

UniProt Primary Accession #

P01587

UniProt Related Accession #

P01587

GenBank Nucleotide #

NM_009969.4

NCBI Official Full Name

granulocyte-macrophage colony-stimulating factor

NCBI Official Synonym Full Names

colony stimulating factor 2 (granulocyte-macrophage)

NCBI Official Symbol

Csf2

NCBI Official Synonym Symbols

CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM

UniProt Protein Name

Granulocyte-macrophage colony-stimulating factor

UniProt Synonym Protein Names

Colony-stimulating factor; CSF

Protein Family

Granulocyte colony-stimulating factor receptor

UniProt Gene Name

Csf2

UniProt Synonym Gene Names

Csfgm; GM-CSF; CSF

NCBI Protein Information

granulocyte-macrophage colony-stimulating factor

UniProt Comments for GM-CSF

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Research Articles on GM-CSF

1. this study demonstrates that epithelial-derived GM-CSF is a critical early signal during allergic sensitization to cockroach allergen

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GM-CSF active protein

Reference Product	PubMed Publications
Il6 active protein	>39 publications with GM-CSF and Il6
Il4 active protein	>22 publications with GM-CSF and Il4
Il2 active protein	>16 publications with GM-CSF and Il2
Il5 active protein	>12 publications with GM-CSF and Il5
Csf2rb active protein	>7 publications with GM-CSF and Csf2rb
Csf2ra active protein	>6 publications with GM-CSF and Csf2ra
Akt1 active protein	>1 publications with GM-CSF and Akt1
Stat5a active protein	>1 publications with GM-CSF and Stat5a
Csf2rb2 active protein	>1 publications with GM-CSF and Csf2rb2

Pathways associated with GM-CSF active protein

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram

Diseases associated with GM-CSF active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>71 publications with GM-CSF and Inflammation
Necrosis Antibodies	>38 publications with GM-CSF and Necrosis
Lung Diseases Antibodies	>20 publications with GM-CSF and Lung Diseases
Carcinoma Antibodies	>12 publications with GM-CSF and Carcinoma
Breast Neoplasms Antibodies	>10 publications with GM-CSF and Breast Neoplasms
Fibrosis Antibodies	>7 publications with GM-CSF and Fibrosis
Arthritis, Rheumatoid Antibodies	>6 publications with GM-CSF and Arthritis, Rheumatoid
Neoplasms, Experimental Antibodies	>6 publications with GM-CSF and Neoplasms, Experimental
Heart Diseases Antibodies	>5 publications with GM-CSF and Heart Diseases
Leukemia, Myeloid, Acute Antibodies	>4 publications with GM-CSF and Leukemia, Myeloid, Acute

Organs/Tissues associated with GM-CSF active protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>24 publications with GM-CSF and Lung