3 ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SNAP25 Recombinant Protein

Name: SNAP25 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203168
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203168

The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters and this protein exists as two alternative… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SNAP25, Recombinant Protein

Full Product Name

SNAP25,1-206aa, Human, E Coli

Product Gene Name

SNAP25 recombinant protein

Product Synonym Names

Synaptosomal-associated protein 25 isoform SNAP25B; FLJ23079; SNAP25; RIC-4; RIC4; SEC9; SNAP; SNAP-25; Synaptosomal-associated protein 25 isoform SNAP25B; Synaptosomal-associated protein 25 isoform SNAP25B SuP; Super protein; bA416N4.2; Bdr; dJ1068F16.2; HGNC:11132; MGC105414; MGC139754; Resistance to inhibitors of cholinesterase 4 homolog; RIC 4; SEC9; SNAP 25; SNAP-25B; SNP 25; SNP25; sp; Synaptosomal associated 25 kDa protein; Synaptosomal associated protein; Synaptosomal associated protein 25; Synaptosomal associated protein 25kDa.

Sequence

MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG

Host

E. coli

Form/Format

Liquid in 25mM Tris pH 7.5, 1mM DTT, 10% glycerol

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at +2°C to +8°C for 1 week.
For long term storage, aliquot and store at -20°C to -80°C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

23 kDa (206 aa), confirmed by MALDI-TOF.

Sequence Positions

1-206aa

OMIM

L19760 mRNA

3D Structure

ModBase 3D Structure for P60880

Tag

Non-Tagged

Product Categories/Family for SNAP25 recombinant protein

Neuroscience

Applications Tested/Suitable for SNAP25 recombinant protein

SDS-PAGE

Product References and Citations for SNAP25 recombinant protein

Tafoya LC., et al. (2006) J. Neurosci. 26 (30):7826-38.; Schulz JR., et al. (1998) J. Biol Chem. 273 (38):24355-9.;

Other Notes

Small volumes of SNAP25 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNAP25 purchase

MBS203168 is a recombinant protein targeting SNAP25. Also known as SNAP25,1-206aa, Human, E Coli. Host: E. coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SNAP25. It may not necessarily be applicable to this product.

NCBI GI #

18765735

NCBI GeneID

6616

NCBI Accession #

NP_570824

UniProt Primary Accession #

P60880

UniProt Secondary Accession #

P13795; P36974; P70557; P70558; Q53EM2; Q5U0B5; Q8IXK3; Q96FM2; B2RAU4; D3DW16; D3DW17

UniProt Related Accession #

P60880

GenBank Nucleotide #

NM_130811.3

NCBI Official Full Name

synaptosomal-associated protein 25 isoform SNAP25B

NCBI Official Synonym Full Names

synaptosome associated protein 25

NCBI Official Symbol

SNAP25

NCBI Official Synonym Symbols

SUP; RIC4; SEC9; SNAP; CMS18; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2

UniProt Protein Name

Synaptosomal-associated protein 25

UniProt Synonym Protein Names

Super protein; SUP; Synaptosomal-associated 25 kDa protein

Protein Family

Synaptosomal-associated protein

UniProt Gene Name

SNAP25

UniProt Synonym Gene Names

SNAP; SNAP-25; SUP

NCBI Protein Information

synaptosomal-associated protein 25

NCBI Summary for SNAP25

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for SNAP25

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

Research Articles on SNAP25

1. Single nucleotide polymorphism in SNAP-25 gene is associated with Attention deficit hyperactivity disorder.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SNAP25 recombinant protein

Reference Product	PubMed Publications
VAMP2 recombinant protein	>115 publications with SNAP25 and VAMP2
STX1A recombinant protein	>110 publications with SNAP25 and STX1A
SYT1 recombinant protein	>43 publications with SNAP25 and SYT1
VAMP3 recombinant protein	>15 publications with SNAP25 and VAMP3
VAMP8 recombinant protein	>8 publications with SNAP25 and VAMP8
CPLX1 recombinant protein	>2 publications with SNAP25 and CPLX1
STX1B recombinant protein	>1 publications with SNAP25 and STX1B

Pathways associated with SNAP25 recombinant protein

Products by Pathway	Pathway Diagram
Acetylcholine Neurotransmitter Release Cycle Pathway antibodies	Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Dopamine Neurotransmitter Release Cycle Pathway antibodies	Dopamine Neurotransmitter Release Cycle Pathway Diagram
Effects Of Botulinum Toxin Pathway antibodies	Effects Of Botulinum Toxin Pathway Diagram
GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies	GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
Glutamate Neurotransmitter Release Cycle Pathway antibodies	Glutamate Neurotransmitter Release Cycle Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Infectious Disease Pathway antibodies	Infectious Disease Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram

Diseases associated with SNAP25 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>174 publications with SNAP25 and Nervous System Diseases
Brain Diseases Antibodies	>120 publications with SNAP25 and Brain Diseases
Paralysis Antibodies	>31 publications with SNAP25 and Paralysis
Pain Antibodies	>28 publications with SNAP25 and Pain
Cognition Disorders Antibodies	>28 publications with SNAP25 and Cognition Disorders
Memory Disorders Antibodies	>24 publications with SNAP25 and Memory Disorders
Seizures Antibodies	>23 publications with SNAP25 and Seizures
Neurobehavioral Manifestations Antibodies	>22 publications with SNAP25 and Neurobehavioral Manifestations
Movement Disorders Antibodies	>21 publications with SNAP25 and Movement Disorders
Poisoning Antibodies	>18 publications with SNAP25 and Poisoning

Organs/Tissues associated with SNAP25 recombinant protein

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>720 publications with SNAP25 and Nerve
Brain Antibodies	>539 publications with SNAP25 and Brain
Pancreas Antibodies	>63 publications with SNAP25 and Pancreas
Muscle Antibodies	>56 publications with SNAP25 and Muscle
Embryonic Tissue Antibodies	>48 publications with SNAP25 and Embryonic Tissue
Eye Antibodies	>42 publications with SNAP25 and Eye
Ganglia Antibodies	>37 publications with SNAP25 and Ganglia
Pituitary Gland Antibodies	>23 publications with SNAP25 and Pituitary Gland
Kidney Antibodies	>18 publications with SNAP25 and Kidney
Adrenal Gland Antibodies	>17 publications with SNAP25 and Adrenal Gland