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N-Acetyltransferase 6 (NAT6) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203177

N-acetyltransferase, also known as FuS2 (NAT6), is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to acrylamines. This enzyme is physically localized in the cytoplasm and its activity has been documented by its feasibility to acetylate… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
N-acetyltransferase 6 (NAT6), Recombinant Protein
Full Product Name
N-acetyltransferase 6, 1-308aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Protein fusion-2; FuS2; FuS-2; NAT6; FuS 2; N acetyltransferase 6; Protein fus 2; Protein fusion 2.
Sequence
MGSSHHHHHH SSGLVPRGSH MQELTLSPGP AKLTPTLDPT HRMELILSTS PAELTLDPAC QPKLPLDSTC QPEMTFNPGP TELTLDPEHQ PEETPAPSLA ELTLEPVHRR PELLDACADL INDQWPRSRT SRLHSLGQSS DAFPLCLMLL SPHPTLEAAP VVVGHARLSR VLNQPQSLLV ETVVVARALR GRGFGRRLME GLEVFARARG FRKLHLTTHD QVHFYTHLGY QLGEPVQGLV FTSRRLPATL LNAFPTAPSP RPPRKAPNLT AQAAPRGPKG PPLPPPPPLP ECLTISPPVP SGPPSKSLLE TQYQNVRGRP IFWMEKDI
Host
E Coli
Form/Format
Liquid. In 20 mM Mes buffer (pH 5.0) containing 150mM NaCl, 30% glycerol.
Purity/Purification
> 95% by SDS-PAGE
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
35.9 kDa (328aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
OMIM
AF040706 mRNA
3D Structure
ModBase 3D Structure for Q93015
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for NAT6 recombinant protein

Applications Tested/Suitable for NAT6 recombinant protein
SDS-PAGE

Product References and Citations for NAT6 recombinant protein

Zegerman P., et al. (2000). Oncogene. 19 (1):161-3.; Gatphayak K., et al. (2004). Gene. 337:105-11;

Other Notes

Small volumes of NAT6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NAT6 purchase

MBS203177 is a recombinant protein targeting NAT6. Also known as N-acetyltransferase 6, 1-308aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NAT6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
N-acetyltransferase 6 isoform 1
NCBI Official Synonym Full Names
N-acetyltransferase 6
NCBI Official Symbol
NAT6
NCBI Official Synonym Symbols
FUS2; FUS-2
UniProt Protein Name
N-acetyltransferase 6
UniProt Synonym Protein Names
Protein fusion-2; Protein fus-2
Protein Family
UniProt Gene Name
NAT6
UniProt Synonym Gene Names
FUS2; Protein fus-2
NCBI Protein Information
N-acetyltransferase 6

NCBI Summary for NAT6

This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
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UniProt Comments for NAT6

Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with NAT6 recombinant protein

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