FABP6 Recombinant Protein

Name: FABP6 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203200
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203200

FABP-6 is a cytosolic protein that binds bile acids with a high affinity. In the small intestine, its expression is restricted to the ileum where it is involved in the enterohepatic circulation of bile acids. Alternate transcription promoters generate two… More details

$245 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FABP6, Recombinant Protein

Full Product Name

FABP6, isoform2, 1-128aa, Human, E Coli

Product Gene Name

FABP6 recombinant protein

Product Synonym Names

Fatty acid binding protein 6; I-BABP; I-15P; ILLBP; ILBP; ILBP3; I-BAP; I-BALB; Fatty acid binding protein 6; Gastrotropin; FABP6; Fatty acid binding protein 6 Fatty acid binding protein 6; ileal (gastrotropin); GT; I 15P; I BABP; I BALB; I BAP; I15P; IBABP; IBALB; IBAP; ILBP; Ileal lipid binding protein; Intestinal 15 kDa protein; Intestinal bile acid binding protein.

Sequence

MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA

Host

E Coli

Form/Format

Liquid in phosphate buffered saline (pH 7.4), 10% glycerol

Purity/Purification

> 95% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

14kDa (128aa), confirmed by MALDI-TOF.

OMIM

U19869 mRNA

Antigen Species

Human

Product Categories/Family for FABP6 recombinant protein

Cell Cycle

Applications Tested/Suitable for FABP6 recombinant protein

SDS-PAGE

Product References and Citations for FABP6 recombinant protein

Ohmachi T., et al. (2006). Clin Cancer Res. Sep 1; 12 (17):5090-5.; Grober J., et al. (1999) J Biol Chem. Oct 15; 274 (42):29749-54.;

Other Notes

Small volumes of FABP6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FABP6 purchase

MBS203200 is a recombinant protein targeting FABP6. Also known as FABP6, isoform2, 1-128aa, Human, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FABP6. It may not necessarily be applicable to this product.

NCBI GI #

18490679

NCBI GeneID

2172

NCBI Accession #

AAH22489

UniProt Secondary Accession #

Q07DR7; Q8TBI3; Q9UGI7

UniProt Related Accession #

P51161

NCBI Official Full Name

FABP6 protein

NCBI Official Synonym Full Names

fatty acid binding protein 6

NCBI Official Symbol

FABP6

NCBI Official Synonym Symbols

ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB

UniProt Protein Name

Gastrotropin

UniProt Synonym Protein Names

Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP

Protein Family

Gastrotropin

UniProt Gene Name

FABP6

UniProt Synonym Gene Names

ILBP; ILLBP; GT; ILBP; I-15P; I-BABP

NCBI Protein Information

gastrotropin

NCBI Summary for FABP6

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for FABP6

Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion ().

Research Articles on FABP6

1. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FABP6 recombinant protein

Reference Product	PubMed Publications
FABP4 recombinant protein	>3 publications with FABP6 and FABP4
SLC10A2 recombinant protein	>2 publications with FABP6 and SLC10A2
LIPE recombinant protein	>1 publications with FABP6 and LIPE
ABCC3 recombinant protein	>1 publications with FABP6 and ABCC3
NR1H4 recombinant protein	>1 publications with FABP6 and NR1H4

Pathways associated with FABP6 recombinant protein

Products by Pathway	Pathway Diagram
Bile Acid And Bile Salt Metabolism Pathway antibodies	Bile Acid And Bile Salt Metabolism Pathway Diagram
Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway antibodies	Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway Diagram
Lipid Digestion, Mobilization, And Transport Pathway antibodies	Lipid Digestion, Mobilization, And Transport Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram
Recycling Of Bile Acids And Salts Pathway antibodies	Recycling Of Bile Acids And Salts Pathway Diagram

Diseases associated with FABP6 recombinant protein

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>10 publications with FABP6 and Fatty Liver
Disease Models, Animal Antibodies	>2 publications with FABP6 and Disease Models, Animal
Colonic Neoplasms Antibodies	>2 publications with FABP6 and Colonic Neoplasms
Obesity Antibodies	>2 publications with FABP6 and Obesity
Liver Neoplasms Antibodies	>1 publications with FABP6 and Liver Neoplasms
Inflammation Antibodies	>1 publications with FABP6 and Inflammation
Atherosclerosis Antibodies	>1 publications with FABP6 and Atherosclerosis
Liver Diseases Antibodies	>1 publications with FABP6 and Liver Diseases
Neoplasms, Experimental Antibodies	>1 publications with FABP6 and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>1 publications with FABP6 and Cell Transformation, Neoplastic

Organs/Tissues associated with FABP6 recombinant protein

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>3 publications with FABP6 and Ovary
Kidney Antibodies	>3 publications with FABP6 and Kidney
Brain Antibodies	>2 publications with FABP6 and Brain
Connective Tissue Antibodies	>2 publications with FABP6 and Connective Tissue
Testis Antibodies	>1 publications with FABP6 and Testis
Lymph Antibodies	>1 publications with FABP6 and Lymph
Eye Antibodies	>1 publications with FABP6 and Eye