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RheB Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203203

Ras homolog enriched in brain (RheB) is a member of the Ras superfamily that was originally identified as an immediate-early gene in brain but is also widely expressed in other tissues. RheB encodes a lipid-anchored, cell membrane protein with five repeats of… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RheB, Recombinant Protein
Full Product Name
RheB, 1-181aa, Human,T7-tag, E Coli
Product Gene Name
Product Synonym Names
Ras homolog enriched in brain; RHEB2; Ras homolog enriched in brain; GTP-binding protein Rheb; RheB; Ras homolog enriched in brain GTP binding protein Rheb; MGC111559; Ras homolog enriched in brain 2; RHEB 2.
Sequence
MASMTGGQQM GRGSASMPQS KSRKIAILGY RSVGKSSLTI QFVEGQFVDS YDPTIENTFT KLITVNGQEY HLQLVDTAGQ DEYSIFPQTY SIDINGYILV YSVTSIKSFE VIKVIHGKLL DMVGKVQIPI MLVGNKKDLH MERVISYEEG KALAESWNAA FLESSAKENQ TAVDVFRRII LEAEKMDGAA SQGKSSC
Host
E Coli
Form/Format
Liquid in 20mM Tris pH 8.0, 1mM DTT, 10% glycerol
Purity/Purification
> 95% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 2-8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Molecular Weight
21.7 kDa (197 aa), confirmed by MALDI-TOF.
OMIM
Z29677 mRNA
3D Structure
ModBase 3D Structure for Q15382
Antigen Species
Human
Tag Information
T7 tag

Product Categories/Family for RheB recombinant protein

Applications Tested/Suitable for RheB recombinant protein
SDS-PAGE

SDS-Page of RheB recombinant protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
RheB Recombinant Protein – Cat# MBS203203

Product References and Citations for RheB recombinant protein

Yamagata K., et al. (1994) J Biol Chem. 269 (23) 16333-9.; Tabancay AP Jr., et al. (2003). J Biol Chem. 278 (41):39921-30.;

Other Notes

Small volumes of RheB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RheB purchase

MBS203203 is a recombinant protein targeting RheB. Also known as RheB, 1-181aa, Human,T7-tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RheB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GTP-binding protein Rheb
NCBI Official Synonym Full Names
Ras homolog, mTORC1 binding
NCBI Official Symbol
RHEB
NCBI Official Synonym Symbols
RHEB2
UniProt Protein Name
GTP-binding protein Rheb
UniProt Synonym Protein Names
Ras homolog enriched in brain
Protein Family
UniProt Gene Name
RHEB
UniProt Synonym Gene Names
RHEB2
NCBI Protein Information
GTP-binding protein Rheb

NCBI Summary for RheB

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]
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UniProt Comments for RheB

Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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