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Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2032700
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MBS2032700 is an antibody targeting PDCD6IP. Also known as Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody. Reactive in Mouse. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP), Polyclonal Antibody
Full Product Name
Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) Polyclonal Antibody
Product Gene Name
anti-PDCD6IP antibody
Product Synonym Names
PDCD6-IP; AIP1; Alix; DRIP4; HP95; ALG-2 Interacting Protein X
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against PDCD6IP. It has been selected for its ability to recognize PDCD6IP in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: PDCD6IP (MBS2032700)
Immunogen: PDCD6IP (MBS2029403)
Matching Pairs
Unconjugated Antibody: PDCD6IP (MBS2032700)
APC-CY7 Conjugated Antibody: PDCD6IP (MBS2053101)
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Molecular Weight
96,773 Da
3D Structure
ModBase 3D Structure for Q9WU78
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunoglobulin Type
IgG
Conjugate
No Conjugate
Cross Reactivity
Mouse
Organism Species
Mouse
Fragment
PDCD6IP (Met1~Lys239)
Quality Control
Content: The quality control contains recombinant PDCD6IP (Met1~Lys239) disposed in loading buffer.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2053103
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PDCD6IP antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-PDCD6IP antibody
Western Blot: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-PDCD6IP antibody

Western Blot: Sample: Mouse Brain Tissue.
Rabbit Anti-PDCD6IP Polyclonal Antibody – Cat# MBS2032700

Western Blot (WB) of anti-PDCD6IP antibody

Western Blot: Sample: Recombinant PDCD6IP, Mouse.
Rabbit Anti-PDCD6IP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2032700

Immunohistochemistry (IHC) of anti-PDCD6IP antibody

DAB staining on IHC-P; Samples: Mouse Uterus Tissue.
Rabbit Anti-PDCD6IP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2032700

Immunohistochemistry (IHC) of anti-PDCD6IP antibody

DAB staining on IHC-P; Samples: Mouse Liver Tissue
Rabbit Anti-PDCD6IP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2032700

Immunohistochemistry (IHC) of anti-PDCD6IP antibody

DAB staining on IHC-P; Samples: Mouse Pancreas Tissue
Rabbit Anti-PDCD6IP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2032700

Other Notes

Small volumes of anti-PDCD6IP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCD6IP. It may not necessarily be applicable to this product.

NCBI GI #
258547152
NCBI GeneID
18571
NCBI Accession #
NP_001158149.1
UniProt Primary Accession #
Q9WU78
UniProt Secondary Accession #
O88695; O89014; Q3TED2; Q8BSL8; Q8R0H5; Q99LR3; Q9QZN8
UniProt Related Accession #
Q9WU78
GenBank Nucleotide #
NM_001164677.1
NCBI Official Full Name
programmed cell death 6-interacting protein isoform 1
NCBI Official Synonym Full Names
programmed cell death 6 interacting protein
NCBI Official Symbol
Pdcd6ip
NCBI Official Synonym Symbols
Aip1; Alix; Eig2; C76364; AI480591; AW544830; mKIAA1375
UniProt Protein Name
Programmed cell death 6-interacting protein
UniProt Synonym Protein Names
ALG-2-interacting protein 1; ALG-2-interacting protein X; E2F1-inducible protein; Eig2
Protein Family
Programmed cell death 6-interacting protein
UniProt Gene Name
Pdcd6ip
UniProt Synonym Gene Names
Aip1; Alix
NCBI Protein Information
programmed cell death 6-interacting protein

UniProt Comments for PDCD6IP

Alix: an adaptor protein that may regulate the function of receptor and cytoskeleton-associated tyrosine kinases. A class E vacuolar protein sorting (VPS) factor involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen. In case of infection, the HIV-1 virus directly takes advantage of its function for viral exocytosis and budding, via its interaction with HIV-1 p6 protein. May play a role in the regulation of both apoptosis and cell proliferation.

Protein type: Adaptor/scaffold; Apoptosis

Chromosomal Location of Human Ortholog: 9|9 F3

Cellular Component: actomyosin; bicellular tight junction; cell junction; cytoplasm; cytoskeleton; cytosol; endoplasmic reticulum exit site; extracellular exosome; extracellular region; Flemming body; focal adhesion; immunological synapse; membrane; myelin sheath

Molecular Function: calcium-dependent protein binding; protein binding; protein dimerization activity; protein homodimerization activity; proteinase activated receptor binding; SH3 domain binding

Biological Process: actomyosin contractile ring assembly; apoptosis; cell cycle; cell division; cell separation after cytokinesis; maintenance of epithelial cell polarity; mitotic cytokinesis; non-lytic virus budding; protein homooligomerization; protein transport; regulation of centrosome duplication; regulation of membrane permeability; transport
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Research Articles on PDCD6IP

1. farnesylation of K-Ras was required for its packaging within extracellular nanovesicles, yet expressing a K-Ras farnesylation mutant did not decrease the number of nanovesicles or the amount of Alix protein released per cell.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PDCD6IP antibody

 Reference Product  PubMed Publications
 Pdcd6 antibody  >16 publications with PDCD6IP and Pdcd6
 Src antibody  >11 publications with PDCD6IP and Src
 Sh3kbp1 antibody  >3 publications with PDCD6IP and Sh3kbp1

Pathways associated with anti-PDCD6IP antibody

 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram

Diseases associated with anti-PDCD6IP antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with PDCD6IP and Neoplasms
 Adenocarcinoma Antibodies  >3 publications with PDCD6IP and Adenocarcinoma
 Carcinoma Antibodies  >3 publications with PDCD6IP and Carcinoma
 Disease Models, Animal Antibodies  >3 publications with PDCD6IP and Disease Models, Animal
 Kidney Diseases Antibodies  >3 publications with PDCD6IP and Kidney Diseases
 Cardiovascular Diseases Antibodies  >1 publications with PDCD6IP and Cardiovascular Diseases
 Myocardial Ischemia Antibodies  >1 publications with PDCD6IP and Myocardial Ischemia
 Sarcoma Antibodies  >1 publications with PDCD6IP and Sarcoma
 Liver Neoplasms Antibodies  >1 publications with PDCD6IP and Liver Neoplasms
 Kidney Neoplasms Antibodies  >1 publications with PDCD6IP and Kidney Neoplasms

Organs/Tissues associated with anti-PDCD6IP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with PDCD6IP and Brain
 Kidney Antibodies  >9 publications with PDCD6IP and Kidney
 Blood Antibodies  >7 publications with PDCD6IP and Blood
 Muscle Antibodies  >3 publications with PDCD6IP and Muscle
 Lung Antibodies  >3 publications with PDCD6IP and Lung
 Heart Antibodies  >2 publications with PDCD6IP and Heart
 Testis Antibodies  >1 publications with PDCD6IP and Testis
 Intestine Antibodies  >1 publications with PDCD6IP and Intestine
 Ovary Antibodies  >1 publications with PDCD6IP and Ovary
 Liver Antibodies  >1 publications with PDCD6IP and Liver
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