uPP1 Recombinant Protein

Name: uPP1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203502
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203502

uridine phosphorylase 1, also known as uPP1 catalyses the reversible phosphorolysis of uridine to uracil. The reaction products are then utilized as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. The expression… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

uPP1, Recombinant Protein

Full Product Name

uPP1, 1-310aa, Human, His tag, E Coli

Product Gene Name

uPP1 recombinant protein

Product Synonym Names

uridine phosphorylase 1; uP; uPASE; uPP; urdPase 1

Sequence

MGSSHHHHHH SSGLVPRGSH MAATGANAEK AESHNDCPVR LLNPNIAKMK EDILYHFNLT TSRHNFPALF GDVKFVCVGG SPSRMKAFIR CVGAELGLDC PGRDYPNICA GTDRYAMYKV GPVLSVSHGM GIPSISIMLH ELIKLLYYAR CSNVTIIRIG TSGGIGLEPG TVVITEQAVD TCFKAEFEQI VLGKRVIRKT DLNKKLVQEL LLCSAELSEF TTVVGNTMCT LDFYEGQGRL DGALCSYTEK DKQAYLEAAY AAGVRNIEME SSVFAAMCSA CGLQAAVVCV TLLNRLEGDQ ISSPRNVLSE YQQRPQRLVS YFIKKKLSKA

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 200mM NaCl

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.25 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

36 kDa (330aa), confirmed by MALDI-TOF

OMIM

X90858 mRNA

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for uPP1 recombinant protein

Cancer

Applications Tested/Suitable for uPP1 recombinant protein

SDS-PAGE

Product References and Citations for uPP1 recombinant protein

Kanzaki A., et al. (2002) Int J Cancer. 97 (5):631-5.; Russll RL., et al. (2001) J Biol Chem. 276 (16):13302-7.;

Other Notes

Small volumes of uPP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for uPP1 purchase

MBS203502 is a recombinant protein targeting uPP1. Also known as uPP1, 1-310aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for uPP1. It may not necessarily be applicable to this product.

NCBI GI #

31742508

NCBI GeneID

7378

NCBI Accession #

NP_853628

UniProt Secondary Accession #

Q15362; D3DVM4

UniProt Related Accession #

Q16831

GenBank Nucleotide #

NM_181597.1

NCBI Official Synonym Full Names

uridine phosphorylase 1

NCBI Official Symbol

UPP1

NCBI Official Synonym Symbols

UP; UPP; UPASE; UDRPASE

UniProt Protein Name

Uridine phosphorylase 1

Protein Family

Uridine phosphorylase

UniProt Gene Name

UPP1

UniProt Synonym Gene Names

UP; UPase 1; UrdPase 1

NCBI Protein Information

uridine phosphorylase 1

NCBI Summary for uPP1

This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]

UniProt Comments for uPP1

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7488099). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Research Articles on uPP1

1. there are inter-ethnic differences for uridine phosphorylase 1 (UPP1) and zinc finger-SWIM containing 4 (ZSWIM4) in response to 1alpha,25(OH)2D3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with uPP1 recombinant protein

Reference Product	PubMed Publications
TYMP recombinant protein	>5 publications with uPP1 and TYMP
DPYD recombinant protein	>2 publications with uPP1 and DPYD

Pathways associated with uPP1 recombinant protein

Products by Pathway	Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Fluoropyrimidine Activity Pathway antibodies	Fluoropyrimidine Activity Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Nucleotides Pathway antibodies	Metabolism Of Nucleotides Pathway Diagram
Pyrimidine Catabolism Pathway antibodies	Pyrimidine Catabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram

Diseases associated with uPP1 recombinant protein

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with uPP1 and Brain Diseases
Disease Models, Animal Antibodies	>1 publications with uPP1 and Disease Models, Animal

Organs/Tissues associated with uPP1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>2 publications with uPP1 and Ovary
Liver Antibodies	>1 publications with uPP1 and Liver
Intestine Antibodies	>1 publications with uPP1 and Intestine
Blood Antibodies	>1 publications with uPP1 and Blood
Brain Antibodies	>1 publications with uPP1 and Brain
Pancreas Antibodies	>1 publications with uPP1 and Pancreas
Lung Antibodies	>1 publications with uPP1 and Lung
Skin Antibodies	>1 publications with uPP1 and Skin