HADH Recombinant Protein

Name: HADH Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203557
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203557

HADH, which belongs to the family of oxidoreductases, is important for converting certain fats to energy. This protein is an enzyme that catalyzes the chemical reaction. ( (S)-3-hydroxyacyl-CoA + NAD+ 3-oxoacyl-CoA + NADH + H+) It is also involved in a… More details

$220 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HADH, Recombinant Protein

Full Product Name

HADH, 13-314aa, Human, His tag, E Coli

Product Gene Name

HADH recombinant protein

Product Synonym Names

Hydroxyacyl-coenzyme A dehydrogenase mitochondrial; HAD; HADH1; HHF4; M/SCHAD; SCHAD; Hydroxyacyl-coenzyme A dehydrogenase; mitochondrial Hydroxyacyl Coenzyme A dehydrogenase type II; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 3 hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type 2; 3 hydroxyacyl CoA dehydrogenase type II; AB binding alcohol dehydrogenase; 17b HSD10; ABAD; Ads9; Amyloid beta binding polypeptide; Amyloid beta peptide binding alcohol dehydrogenase; Amyloid beta peptide binding protein; CAMR; DuPXp11.22; Endoplasmic Reticulum Amyloid Binding Protein; Endoplasmic reticulum associated amyloid beta peptide binding protein; ER associated a+myloid beta-binding protein; ERAB; HADH 2; HADH2; HCD 2; HCD2; HSD17B10; Hydroxyacyl CoA Dehydrogenase type II; Hydroxysteroid (17 beta) dehydrogenase 10; Mental retardation X linked syndromic 11; MHBD; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; MRPP2; MRX17; Short chain dehydrogenase/reductase family 5C member 1; SDR5C1; Short chain L 3 hydroxyacyl CoA dehydrogenase type 2; Short chain type dehydrogenase/reductase XH98G2; Type 10 17b HSD; Type 10 17beta hydroxysteroid dehydrogenase; Type II HADH; XH98G2.

Sequence

MGSSHHHHHH SSGLVPRGSH MSSSSTASAS AKKIIVKHVT VIGGGLMGAG IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENPKAGDE FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ KTFESLVDFS KALGKHPVSC KDTPGFIVNR LLVPYLMEAI RLYERGDASK EDIDTAMKLG AGYPMGPFEL LDYVGLDTTK FIVDGWHEMD AENPLHQPSP SLNKLVAENK FGKKTGEGFY KYK

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl

Purity/Purification

> 95% by SDS-PAGE

Concentration

1.0 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

35.1 kDa (323aa), confirmed by MALDI-TOF.

OMIM

X96752 mRNA

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for HADH recombinant protein

Metabolism

Applications Tested/Suitable for HADH recombinant protein

SDS-PAGE

Product References and Citations for HADH recombinant protein

Tieu K, et al. (2004) Ann Neurol. 56 (1):51-60; Vredendaal PJ, et al. (1996) Biochem Biophys Res Commun. 223 (3):718-23.;

Other Notes

Small volumes of HADH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HADH purchase

MBS203557 is a recombinant protein targeting HADH. Also known as HADH, 13-314aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HADH. It may not necessarily be applicable to this product.

NCBI GI #

12653081

NCBI GeneID

3033

NCBI Accession #

AAH00306

UniProt Secondary Accession #

O00324; O00397; O00753; Q4W5B4; J3KQ17

UniProt Related Accession #

Q16836

NCBI Official Full Name

Hydroxyacyl-Coenzyme A dehydrogenase

NCBI Official Synonym Full Names

hydroxyacyl-CoA dehydrogenase

NCBI Official Symbol

HADH

NCBI Official Synonym Symbols

HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD

UniProt Protein Name

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

UniProt Synonym Protein Names

Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase

Protein Family

Hydroxyacyl-coenzyme A dehydrogenase

UniProt Gene Name

HADH

UniProt Synonym Gene Names

HAD; HADHSC; SCHAD; HCDH

NCBI Protein Information

hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

NCBI Summary for HADH

This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]

UniProt Comments for HADH

Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.

Research Articles on HADH

1. The most frequently seen mutations in Turkish patients with congenital hyperinsulinism (CHI) were ATP binding cassette subfamily C member 8 (ABCC8) gene, followed by 3-hydroxyacyl CoA dehydrogenase (HADH) and kcnj11 channel (KCNJ11) genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HADH recombinant protein

Products by Pathway	Pathway Diagram
Amino Acid Metabolism Pathway antibodies	Amino Acid Metabolism Pathway Diagram
Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway antibodies	Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway Diagram
Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway antibodies	Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway Diagram
Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway antibodies	Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway Diagram
Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway antibodies	Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway Diagram
Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway antibodies	Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies	FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram

Diseases associated with HADH recombinant protein

Disease Name	Pubmed Publications
Obesity Antibodies	>14 publications with HADH and Obesity
Fatty Liver Antibodies	>7 publications with HADH and Fatty Liver
Disease Models, Animal Antibodies	>7 publications with HADH and Disease Models, Animal
Cardiovascular Diseases Antibodies	>6 publications with HADH and Cardiovascular Diseases
Weight Loss Antibodies	>6 publications with HADH and Weight Loss
3-Hydroxyacyl-CoA Dehydrogenase Deficiency Antibodies	>5 publications with HADH and 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
Heart Diseases Antibodies	>4 publications with HADH and Heart Diseases
Hyperplasia Antibodies	>3 publications with HADH and Hyperplasia
Inflammation Antibodies	>2 publications with HADH and Inflammation
Liver Diseases Antibodies	>1 publications with HADH and Liver Diseases

Organs/Tissues associated with HADH recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>62 publications with HADH and Muscle
Blood Antibodies	>27 publications with HADH and Blood
Brain Antibodies	>18 publications with HADH and Brain
Liver Antibodies	>16 publications with HADH and Liver
Pancreas Antibodies	>12 publications with HADH and Pancreas
Adipose Tissue Antibodies	>10 publications with HADH and Adipose Tissue
Heart Antibodies	>9 publications with HADH and Heart
Connective Tissue Antibodies	>8 publications with HADH and Connective Tissue
Lung Antibodies	>4 publications with HADH and Lung
Kidney Antibodies	>4 publications with HADH and Kidney