• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NTAL Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203662

NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells,… More details

$220 / 0.02 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NTAL, Recombinant Protein
Full Product Name
NTAL, 27-243aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Non-T-cell activation linker; LAT2; HSPC046; LAB; WBSCR15; WBSCR5; WSCR5; Non-T-cell activation linker LAB; Lat2; Linker for activation of B cells; Linker for activation of T cells family member 2; Membrane associated adapter molecule; Non T cell activation linker; WBSCR 5; Wbscr15; Williams Beuren syndrome chromosome region 15; Williams Beuren syndrome chromosome region 5
Sequence
MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA
Host
E Coli
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Purity/Purification
> 80% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
26.2 kDa (238aa), confirmed by MALDI-TOF
OMIM
AF257135 mRNA
3D Structure
ModBase 3D Structure for Q9GZY6
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for NTAL recombinant protein

Applications Tested/Suitable for NTAL recombinant protein
SDS-PAGE

Product References and Citations for NTAL recombinant protein

Naumann M., et al. (2010) Cell Signal. 22 (3):395-403.; Gilfillan AM., et al. (2008). Int J Biochem Cell Biol. 39 (5): 868-873.;

Other Notes

Small volumes of NTAL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NTAL purchase

MBS203662 is a recombinant protein targeting NTAL. Also known as NTAL, 27-243aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NTAL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
linker for activation of T-cells family member 2
NCBI Official Synonym Full Names
linker for activation of T cells family member 2
NCBI Official Symbol
LAT2
NCBI Official Synonym Symbols
LAB; NTAL; WSCR5; WBSCR5; HSPC046; WBSCR15
UniProt Protein Name
Linker for activation of T-cells family member 2
UniProt Synonym Protein Names
Linker for activation of B-cells; Membrane-associated adapter molecule; Non-T-cell activation linker; Williams-Beuren syndrome chromosomal region 15 protein; Williams-Beuren syndrome chromosomal region 5 protein
UniProt Gene Name
LAT2
UniProt Synonym Gene Names
LAB; NTAL; WBS15; WBSCR15; WBSCR5
NCBI Protein Information
linker for activation of T-cells family member 2

NCBI Summary for NTAL

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]

UniProt Comments for NTAL

Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000