RGS19 Recombinant Protein

Name: RGS19 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203945
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203945

RGS19, also known as Regulator of G-protein signaling 19, belongs to RGS (regulator of G protein signaling) family and negatively regulates G protein coupled receptor signaling. This protein specifically interacts with heterotrimeric GTP-binding protein G… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RGS19, Recombinant Protein

Full Product Name

RGS19, 1-217aa, Human, His tag, E Coli

Product Gene Name

RGS19 recombinant protein

Product Synonym Names

Regulator of G-protein signaling 19; GAIP; GNAI3IP

Sequence

MGSSHHHHHH SSGLVPRGSH MPTPHEAEKQ ITGPEEADRP PSMSSHDTAS PAAPSRNPCC LCWCCCCSCS WNQERRRAWQ ASRESKLQPL PSCEVCATPS PEEVQSWAQS FDKLMHSPAG RSVFRAFLRT EYSEENMLFW LACEELKAEA NQHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINKKMQ EPSAHTFDDA QLQIYTLMHR DSYPRFLSSP TYRALLLQGP SQSSSEA

Host

E Coli

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

26.7 kDa (237aa), confirmed by MALDI-TOF

OMIM

X91809 mRNA

3D Structure

ModBase 3D Structure for P49795

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RGS19 recombinant protein

Cancer

Applications Tested/Suitable for RGS19 recombinant protein

SDS-PAGE

Product References and Citations for RGS19 recombinant protein

Wong YH., et al. (2010) Cell Signal. 22 (11):1700-7.; Farquhar MG., et al (1995) Proc Natl Acad Sci u S A. 92 (25):11916-20.

Other Notes

Small volumes of RGS19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RGS19 purchase

MBS203945 is a recombinant protein targeting RGS19. Also known as RGS19, 1-217aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS19. It may not necessarily be applicable to this product.

NCBI GI #

86990435

NCBI GeneID

10287

NCBI Accession #

NP_001034556

UniProt Primary Accession #

P49795

UniProt Secondary Accession #

Q53XN0; Q8TD60; A8K216; E1P5G9

UniProt Related Accession #

P49795

GenBank Nucleotide #

NM_001039467.1

NCBI Official Full Name

regulator of G-protein signaling 19

NCBI Official Synonym Full Names

regulator of G protein signaling 19

NCBI Official Symbol

RGS19

NCBI Official Synonym Symbols

GAIP; RGSGAIP

UniProt Protein Name

Regulator of G-protein signaling 19

UniProt Synonym Protein Names

G-alpha-interacting protein; GAIP

Protein Family

Regulator of G-protein signaling

UniProt Gene Name

RGS19

UniProt Synonym Gene Names

GAIP; GNAI3IP; RGS19; GAIP

NCBI Protein Information

regulator of G-protein signaling 19

NCBI Summary for RGS19

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for RGS19

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

Research Articles on RGS19

1. RGS19 senses cellular iron availability and is stabilized under iron-depleted conditions, resulting in the induction of a growth-inhibitory signal.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RGS19 recombinant protein

Reference Product	PubMed Publications
GIPC1 recombinant protein	>8 publications with RGS19 and GIPC1
GNAI3 recombinant protein	>4 publications with RGS19 and GNAI3
GNA14 recombinant protein	>1 publications with RGS19 and GNA14
GNAI1 recombinant protein	>1 publications with RGS19 and GNAI1

Pathways associated with RGS19 recombinant protein

Products by Pathway	Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
G Alpha (z) Signalling Events Pathway antibodies	G Alpha (z) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies	Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with RGS19 recombinant protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>2 publications with RGS19 and Breast Neoplasms
Ovarian Neoplasms Antibodies	>2 publications with RGS19 and Ovarian Neoplasms
Cell Transformation, Neoplastic Antibodies	>2 publications with RGS19 and Cell Transformation, Neoplastic
Nervous System Diseases Antibodies	>1 publications with RGS19 and Nervous System Diseases
Hypertension Antibodies	>1 publications with RGS19 and Hypertension
Lung Neoplasms Antibodies	>1 publications with RGS19 and Lung Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with RGS19 and Carcinoma, Hepatocellular
Necrosis Antibodies	>1 publications with RGS19 and Necrosis

Organs/Tissues associated with RGS19 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with RGS19 and Brain
Blood Antibodies	>6 publications with RGS19 and Blood
Bone Antibodies	>4 publications with RGS19 and Bone
Lung Antibodies	>3 publications with RGS19 and Lung
Embryonic Tissue Antibodies	>2 publications with RGS19 and Embryonic Tissue
Kidney Antibodies	>2 publications with RGS19 and Kidney
Heart Antibodies	>1 publications with RGS19 and Heart
Eye Antibodies	>1 publications with RGS19 and Eye
Prostate Antibodies	>1 publications with RGS19 and Prostate
Liver Antibodies	>1 publications with RGS19 and Liver