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ARL2BP Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203951

ARL2BP is an effector of ADP-ribosylation factor-like 2 (ARL2) that is essential for nuclear retention of STAT3. This protein binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. Though predominantly… More details

$230 / 0.02 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARL2BP, Recombinant Protein
Full Product Name
ARL2BP, 1-163aa, Human, His tag, E Coli
Product Synonym Names
ADP-ribosylation factor-like 2 binding protein; BART; BART1
Sequence
MGSSHHHHHH SSGLVPRGSH MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH
Host
E Coli
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 10% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
20.9 kDa (183aa), confirmed by MALDI-TOF
OMIM
AF126062 mRNA
3D Structure
ModBase 3D Structure for Q9Y2Y0
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for ARL2BP recombinant protein

Applications Tested/Suitable for ARL2BP recombinant protein
SDS-PAGE

Product References and Citations for ARL2BP recombinant protein

Ding J., et al (2009) Structure. 17 (4):602-10.; Kahn RA., et al. (1999) J Biol Chem. 274 (39):27553-61.;

Other Notes

Small volumes of ARL2BP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARL2BP purchase

MBS203951 is a recombinant protein targeting ARL2BP. Also known as ARL2BP, 1-163aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ARL2BP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ADP-ribosylation factor-like protein 2-binding protein
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 2 binding protein
NCBI Official Symbol
ARL2BP
NCBI Official Synonym Symbols
BART; RP66; BART1
UniProt Protein Name
ADP-ribosylation factor-like protein 2-binding protein
UniProt Synonym Protein Names
Binder of ARF2 protein 1
UniProt Gene Name
ARL2BP
UniProt Synonym Gene Names
BART; BART1; ARF-like 2-binding protein; ARL2-binding protein
NCBI Protein Information
ADP-ribosylation factor-like protein 2-binding protein

NCBI Summary for ARL2BP

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for ARL2BP

Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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