RCN2 Recombinant Protein

Name: RCN2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS203983
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS203983

RCN2, also known as reticulocalbin-2, is belongs to the CREC protein family. RCN2 is a calcium-binding protein located in the lumen of the ER. This protein contains six conserved regions with similarity to a high affinity Ca (+2)-binding motif, the EF-hand.… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RCN2, Recombinant Protein

Full Product Name

RCN2, 26-317aa, Human, His tag, E Coli

Product Gene Name

RCN2 recombinant protein

Product Synonym Names

Reticulocalbin-2; E6BP; ERC55

Sequence

MGSSHHHHHH SSGLVPRGSH MEELHYPLGE RRSDYDREAL LGVQEDVDEY VKLGHEEQQK RLQAIIKKID LDSDGFLTES ELSSWIQMSF KHYAMQEAKQ QFVEYDKNSD DTVTWDEYNI QMYDRVIDFD ENTALDDAEE ESFRKLHLKD KKRFEKANQD SGPGLSLEEF IAFEHPEEVD YMTEFVIQEA LEEHDKNGDG FVSLEEFLGD YRWDPTANED PEWILVEKDR FVNDYDKDND GRLDPQELLP WVVPNNQGIA QEEALHLIDE MDLNGDKKLS EEEILENPDL FLTSEATDYG RQLHDDYFYH DEL

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

36.8 kDa (313aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

OMIM

X78669 mRNA

3D Structure

ModBase 3D Structure for Q14257

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RCN2 recombinant protein

Signal Transduction

Applications Tested/Suitable for RCN2 recombinant protein

SDS-PAGE

Product References and Citations for RCN2 recombinant protein

Ludvigsen M, et al. (2009) Proteomics. 9 (23):5267-87; Wang JY, et al. (1997) Cytogenet Cell Genet. 79 (1-2):60-1

Other Notes

Small volumes of RCN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RCN2 purchase

MBS203983 is a recombinant protein targeting RCN2. Also known as RCN2, 26-317aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RCN2. It may not necessarily be applicable to this product.

NCBI GI #

4506457

NCBI GeneID

5955

NCBI Accession #

NP_002893

UniProt Primary Accession #

Q14257

UniProt Secondary Accession #

Q53XN8; A8MTG6; F8WCY5

UniProt Related Accession #

Q14257

GenBank Nucleotide #

NM_002902.2

NCBI Official Full Name

reticulocalbin-2 isoform a

NCBI Official Synonym Full Names

reticulocalbin 2

NCBI Official Symbol

RCN2

NCBI Official Synonym Symbols

E6BP; ERC55; ERC-55; TCBP49

UniProt Protein Name

Reticulocalbin-2

UniProt Synonym Protein Names

Calcium-binding protein ERC-55; E6-binding protein; E6BP

Protein Family

Regulator of calcineurin

UniProt Gene Name

RCN2

UniProt Synonym Gene Names

ERC55; E6BP

NCBI Protein Information

reticulocalbin-2

NCBI Summary for RCN2

The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

UniProt Comments for RCN2

Not known. Binds calcium.

Research Articles on RCN2

1. RCN2 plays a pivotal role in hepatocellular carcinoma cell proliferation and tumor growth presumably through regulating activation of the EGFR-ERK pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RCN2 recombinant protein

Reference Product	PubMed Publications
UBE3A recombinant protein	>1 publications with RCN2 and UBE3A

Diseases associated with RCN2 recombinant protein

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>4 publications with RCN2 and Cell Transformation, Neoplastic
Brain Diseases Antibodies	>1 publications with RCN2 and Brain Diseases
Nervous System Diseases Antibodies	>1 publications with RCN2 and Nervous System Diseases
Hypertension Antibodies	>1 publications with RCN2 and Hypertension
Disease Models, Animal Antibodies	>1 publications with RCN2 and Disease Models, Animal
Carcinoma, Hepatocellular Antibodies	>1 publications with RCN2 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with RCN2 and Liver Neoplasms
Liver Diseases Antibodies	>1 publications with RCN2 and Liver Diseases

Organs/Tissues associated with RCN2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with RCN2 and Blood
Muscle Antibodies	>2 publications with RCN2 and Muscle
Heart Antibodies	>2 publications with RCN2 and Heart
Liver Antibodies	>1 publications with RCN2 and Liver
Mammary Gland Antibodies	>1 publications with RCN2 and Mammary Gland
Prostate Antibodies	>1 publications with RCN2 and Prostate
Lung Antibodies	>1 publications with RCN2 and Lung
Uncharacterized Tissue Antibodies	>1 publications with RCN2 and Uncharacterized Tissue
Embryonic Tissue Antibodies	>1 publications with RCN2 and Embryonic Tissue
Cervix Antibodies	>1 publications with RCN2 and Cervix