ALDOB Recombinant Protein

Name: ALDOB Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204182
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204182

Fructose-bisphosphate aldolase B, also known as ALDOB, is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. ALDOB catalyzes the reversible cleavage of fructose 1-phosphate… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ALDOB, Recombinant Protein

Full Product Name

ALDOB, 1-364aa, Human, His tag, E Coli

Product Gene Name

ALDOB recombinant protein

Product Synonym Names

Fructose-bisphosphate aldolase B; ALDB; ALDO2; Fructose bisphosphate aldolase B

Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAHRFP ALTQEQKKEL SEIAQSIVAN GKGILAADES VGTMGNRLQR IKVENTEENR RQFREILFSV DSSINQSIGG VILFHETLYQ KDSQGKLFRN ILKEKGIVVG IKLDQGGAPL AGTNKETTIQ GLDGLSERCA QYKKDGVDFG KWRAVLRIAD QCPSSLAIQE NANALARYAS ICQQNGLVPI VEPEVIPDGD HDLEHCQYVT EKVLAAVYKA LNDHHVYLEG TLLKPNMVTA GHACTKKYTP EQVAMATVTA LHRTVPAAVP GICFLSGGMS EEDATLNLNA INLCPLPKPW KLSFSYGRAL QASALAAWGG KAANKEATQE AFMKRAMANC QAAKGQYVHT GSSGAASTQS LFTACYTY

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Purity/Purification

> 95% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

42 kDa (388aa) confirmed by MALDI-TOF

OMIM

X02747 mRNA

3D Structure

ModBase 3D Structure for P05062

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for ALDOB recombinant protein

Metabolism

Applications Tested/Suitable for ALDOB recombinant protein

SDS-PAGE

Product References and Citations for ALDOB recombinant protein

Caffe A R., et al. (1994) J Comp Neurol. 348:291-297.; Dehnes Y., et al. (1998) J Neurosci. 18:3606-3619.

Other Notes

Small volumes of ALDOB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDOB purchase

MBS204182 is a recombinant protein targeting ALDOB. Also known as ALDOB, 1-364aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDOB. It may not necessarily be applicable to this product.

NCBI GI #

40354205

NCBI GeneID

229

NCBI Accession #

NP_000026

UniProt Primary Accession #

P05062

UniProt Secondary Accession #

Q13741; Q13742; Q5T7D6

UniProt Related Accession #

P05062

GenBank Nucleotide #

NM_000035.3

NCBI Official Full Name

fructose-bisphosphate aldolase B

NCBI Official Synonym Full Names

aldolase, fructose-bisphosphate B

NCBI Official Symbol

ALDOB

NCBI Official Synonym Symbols

ALDB; ALDO2

UniProt Protein Name

Fructose-bisphosphate aldolase B

UniProt Synonym Protein Names

Liver-type aldolase

Protein Family

Fructose-bisphosphate aldolase

UniProt Gene Name

ALDOB

UniProt Synonym Gene Names

ALDB

NCBI Protein Information

fructose-bisphosphate aldolase B

NCBI Summary for ALDOB

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]

UniProt Comments for ALDOB

MiscellaneousIn vertebrates, 3 forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.

Research Articles on ALDOB

1. Silencing Aldolase B activated epithelial markers and repressed mesenchymal markers, indicating inactivation of Aldolase B may lead to inhibition of epithelial-mesenchymal transition

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ALDOB recombinant protein

Reference Product	PubMed Publications
FBP1 recombinant protein	>4 publications with ALDOB and FBP1
GAPDH recombinant protein	>2 publications with ALDOB and GAPDH
PKLR recombinant protein	>1 publications with ALDOB and PKLR
PFKP recombinant protein	>1 publications with ALDOB and PFKP

Pathways associated with ALDOB recombinant protein

Products by Pathway	Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies	FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Fructose Catabolism Pathway antibodies	Fructose Catabolism Pathway Diagram
Fructose Metabolism Pathway antibodies	Fructose Metabolism Pathway Diagram
Gluconeogenesis Pathway antibodies	Gluconeogenesis Pathway Diagram

Diseases associated with ALDOB recombinant protein

Disease Name	Pubmed Publications
Fructose Intolerance Antibodies	>17 publications with ALDOB and Fructose Intolerance
Liver Diseases Antibodies	>10 publications with ALDOB and Liver Diseases
Liver Neoplasms Antibodies	>7 publications with ALDOB and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>6 publications with ALDOB and Carcinoma, Hepatocellular
Fatty Liver Antibodies	>4 publications with ALDOB and Fatty Liver
Inflammation Antibodies	>3 publications with ALDOB and Inflammation
Congenital Abnormalities Antibodies	>3 publications with ALDOB and Congenital Abnormalities
Fibrosis Antibodies	>2 publications with ALDOB and Fibrosis
Hepatomegaly Antibodies	>2 publications with ALDOB and Hepatomegaly
Kidney Diseases Antibodies	>1 publications with ALDOB and Kidney Diseases

Organs/Tissues associated with ALDOB recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>26 publications with ALDOB and Liver
Muscle Antibodies	>5 publications with ALDOB and Muscle
Kidney Antibodies	>5 publications with ALDOB and Kidney
Lung Antibodies	>1 publications with ALDOB and Lung
Spleen Antibodies	>1 publications with ALDOB and Spleen