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RTN4IP1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204283

RTN4IP1 is a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for… More details

$230 / 0.02 mg +1 FREE 8GB USB
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RTN4IP1, Recombinant Protein
Full Product Name
RTN4IP1, 41-396aa, Human, His tag E Coli
Product Synonym Names
Reticulon-4-interacting protein 1; MGC12934; NIMP; Reticulon 4 interacting protein 1
Sequence
MGSSHHHHHH SSGLVPRGSH MGSTVMPAWV IDKYGKNEVL RFTQNMMMPI IHYPNEVIVK VHAASVNPID VNMRSGYGAT ALNMKRDPLH VKIKGEEFPL TLGRDVSGVV MECGLDVKYF KPGDEVWAAV PPWKQGTLSE FVVVSGNEVS HKPKSLTHTQ AASLPYVALT AWSAINKVGG LNDKNCTGKR VLILGASGGV GTFAIQVMKA WDAHVTAVCS QDASELVRKL GADDVIDYKS GSVEEQLKSL KPFDFILDNV GGSTETWAPD FLKKWSGATY VTLVTPFLLN MDRLGIADGM LQTGVTVGSK ALKHFWKGVH YRWAFFMASG PCLDDIAELV DAGKIRPVIE QTFPFSKVPE AFLKVERGHA RGKTVINVV
Host
E Coli
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
Purity/Purification
> 95% by SDS-PAGE
Concentration
1.0 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
41.4 kDa (379aa), confirmed by MALDI-TOF
OMIM
AF439711 mRNA
3D Structure
ModBase 3D Structure for Q8WWV3
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for RTN4IP1 recombinant protein

Applications Tested/Suitable for RTN4IP1 recombinant protein
SDS-PAGE

Product References and Citations for RTN4IP1 recombinant protein

Huber A.B. et al. (2000) Biol. Chem. 381: 407-419.; Hu W.H. et al. (2002) J. Neurochem. 81: 36-45.

Other Notes

Small volumes of RTN4IP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RTN4IP1 purchase

MBS204283 is a recombinant protein targeting RTN4IP1. Also known as RTN4IP1, 41-396aa, Human, His tag E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RTN4IP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
reticulon-4-interacting protein 1, mitochondrial isoform 1
NCBI Official Synonym Full Names
reticulon 4 interacting protein 1
NCBI Official Symbol
RTN4IP1
NCBI Official Synonym Symbols
NIMP; OPA10
UniProt Protein Name
Reticulon-4-interacting protein 1, mitochondrial
UniProt Synonym Protein Names
NOGO-interacting mitochondrial protein
UniProt Gene Name
RTN4IP1
UniProt Synonym Gene Names
NIMP
NCBI Protein Information
reticulon-4-interacting protein 1, mitochondrial

NCBI Summary for RTN4IP1

This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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UniProt Comments for RTN4IP1

Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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