RhoG Recombinant Protein

Name: RhoG Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204292
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204292

RhoG (Ras homology Growth-related) is a member of the Rac subfamily of the Rho family of small G proteins. RhoG is a small monomeric GTP-binding protein (G protein), and is an important component of many intracellular signalling pathways. This protien are… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RhoG, Recombinant Protein

Full Product Name

RhoG, 1-188aa, Human, His tag, E Coli

Product Gene Name

RhoG recombinant protein

Product Synonym Names

Rho-related GTP-binding protein RhoG; ARHG

Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMQS IKCVVVGDGA VGKTCLLICY TTNAFPKEYI PTVFDNYSAQ SAVDGRTVNL NLWDTAGQEE YDRLRTLSYP QTNVFVICFS IASPPSYENV RHKWHPEVCH HCPDVPILLV GTKKDLRAQP DTLRRLKEQG QAPITPQQGQ ALAKQIHAVR YLECSALQQD GVKEVFAEAV RAVLNPTPIK RGRSC

Host

E Coli

Form/Format

Liquid. In 20 mM Tris-HCl Buffer, pH8.0, 40% glycerol, 5mM DTT, 200mM NaCl

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.25mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

25.2kDa (225aa) confirmed by MALDI-TOF

OMIM

L11317 mRNA

3D Structure

ModBase 3D Structure for P84095

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RhoG recombinant protein

Signal Transduction

Applications Tested/Suitable for RhoG recombinant protein

SDS-PAGE

Product References and Citations for RhoG recombinant protein

van Buul J.D., et al. (2007) J. Cell Biol. 178:1279-1293; Ellerbroek S.M., et al. (2004) Mol. Biol. Cell 15:3309-3319

Other Notes

Small volumes of RhoG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RhoG purchase

MBS204292 is a recombinant protein targeting RhoG. Also known as RhoG, 1-188aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RhoG. It may not necessarily be applicable to this product.

NCBI GI #

46249393

NCBI GeneID

391

NCBI Accession #

NP_001656

UniProt Primary Accession #

P84095

UniProt Secondary Accession #

P35238; Q8NI04

UniProt Related Accession #

P84095

GenBank Nucleotide #

NM_001665.3

NCBI Official Full Name

rho-related GTP-binding protein RhoG

NCBI Official Synonym Full Names

ras homolog family member G

NCBI Official Symbol

RHOG

NCBI Official Synonym Symbols

ARHG

UniProt Protein Name

Rho-related GTP-binding protein RhoG

Protein Family

Rho-related GTP-binding protein

UniProt Gene Name

RHOG

UniProt Synonym Gene Names

ARHG

NCBI Protein Information

rho-related GTP-binding protein RhoG

NCBI Summary for RhoG

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011]

UniProt Comments for RhoG

Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.

Research Articles on RhoG

1. RhoG and SGEF modulate the phosphorylation of paxillin, which plays a key role during invadopodia disassembly.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RhoG recombinant protein

Reference Product	PubMed Publications
ELMO1 recombinant protein	>14 publications with RhoG and ELMO1
DOCK1 recombinant protein	>12 publications with RhoG and DOCK1
ELMO2 recombinant protein	>8 publications with RhoG and ELMO2
ARHGDIA recombinant protein	>4 publications with RhoG and ARHGDIA
KTN1 recombinant protein	>1 publications with RhoG and KTN1
ARHGDIB recombinant protein	>1 publications with RhoG and ARHGDIB
MCF2 recombinant protein	>1 publications with RhoG and MCF2
ARHGDIG recombinant protein	>1 publications with RhoG and ARHGDIG

Pathways associated with RhoG recombinant protein

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Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway antibodies	Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPVI-mediated Activation Cascade Pathway antibodies	GPVI-mediated Activation Cascade Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram

Diseases associated with RhoG recombinant protein

Disease Name	Pubmed Publications
Vascular Diseases Antibodies	>14 publications with RhoG and Vascular Diseases
Necrosis Antibodies	>14 publications with RhoG and Necrosis
Inflammation Antibodies	>11 publications with RhoG and Inflammation
Immune System Diseases Antibodies	>8 publications with RhoG and Immune System Diseases
Hypertension Antibodies	>7 publications with RhoG and Hypertension
Diabetes Mellitus Antibodies	>6 publications with RhoG and Diabetes Mellitus
Breast Neoplasms Antibodies	>6 publications with RhoG and Breast Neoplasms
Atherosclerosis Antibodies	>5 publications with RhoG and Atherosclerosis
Cell Transformation, Neoplastic Antibodies	>5 publications with RhoG and Cell Transformation, Neoplastic
Carcinoma Antibodies	>4 publications with RhoG and Carcinoma

Organs/Tissues associated with RhoG recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>70 publications with RhoG and Blood
Brain Antibodies	>25 publications with RhoG and Brain
Bone Antibodies	>16 publications with RhoG and Bone
Heart Antibodies	>14 publications with RhoG and Heart
Kidney Antibodies	>14 publications with RhoG and Kidney
Muscle Antibodies	>7 publications with RhoG and Muscle
Eye Antibodies	>5 publications with RhoG and Eye
Lung Antibodies	>5 publications with RhoG and Lung
Connective Tissue Antibodies	>5 publications with RhoG and Connective Tissue
Skin Antibodies	>5 publications with RhoG and Skin