YEATS4 Recombinant Protein

Name: YEATS4 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204374
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204374

YEATS4 has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is… More details

$250 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

YEATS4, Recombinant Protein

Full Product Name

YEATS4, 1-227aa, Human, His tag E Coli

Product Gene Name

YEATS4 recombinant protein

Product Synonym Names

YEATS domain-containing protein 4; 4930573H17Rik; B230215M10Rik; GAS41; NuBI-1,YAF9; YEATS domain containing 4; Glioma-amplified sequence 41

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMFKRMAE FGPDSGGRVK GVTIVKPIVY GNVARYFGKK REEDGHTHQW TVYVKPYRNE DMSAYVKKIQ FKLHESYGNP LRVVTKPPYE ITETGWGEFE IIIKIFFIDP NERPVTLYHL LKLFQSDTNA MLGKKTVVSE FYDEMIFQDP TAMMQQLLTT SRQLTLGAYK HETEFAELEV KTREKLEAAK KKTSFEIAEL KERLKASRET INCLKNEIRK LEEDDQAKDI

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 7.5) containing 50% glycerol, 2mM DTT, 0.2M NaCl, 0.1mM PMSF, 50mM Imidazole

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

28.9 kDa (250aa), confirmed by MALDI-TOF

OMIM

U61384 mRNA

3D Structure

ModBase 3D Structure for O95619

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for YEATS4 recombinant protein

Transcription & Translation

Applications Tested/Suitable for YEATS4 recombinant protein

SDS-PAGE

Product References and Citations for YEATS4 recombinant protein

Harborth J. et al. (2000) J. Biol. Chem. 275:31979-31985.; Debernardi S. et al. (2002) Blood. 99: 275-81.

Other Notes

Small volumes of YEATS4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YEATS4 purchase

MBS204374 is a recombinant protein targeting YEATS4. Also known as YEATS4, 1-227aa, Human, His tag E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for YEATS4. It may not necessarily be applicable to this product.

NCBI GI #

5729838

NCBI GeneID

8089

NCBI Accession #

NP_006521

UniProt Primary Accession #

O95619

UniProt Secondary Accession #

Q9NQD0

UniProt Related Accession #

O95619

GenBank Nucleotide #

NM_006530.3

NCBI Official Full Name

YEATS domain-containing protein 4 isoform 1

NCBI Official Synonym Full Names

YEATS domain containing 4

NCBI Official Symbol

YEATS4

NCBI Official Synonym Symbols

YAF9; GAS41; NUBI-1; 4930573H17Rik; B230215M10Rik

UniProt Protein Name

YEATS domain-containing protein 4

UniProt Synonym Protein Names

Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1

Protein Family

YEATS domain-containing protein

UniProt Gene Name

YEATS4

UniProt Synonym Gene Names

GAS41; Gas41; NuBI-1; NuBI1

NCBI Protein Information

YEATS domain-containing protein 4

NCBI Summary for YEATS4

The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

UniProt Comments for YEATS4

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Research Articles on YEATS4

1. identified GAS41 as a novel target for endogenous miR-203 and demonstrate an inverse correlation of miR-203 expression with GAS41 in glioma cell lines

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with YEATS4 recombinant protein

Reference Product	PubMed Publications
KAT5 recombinant protein	>1 publications with YEATS4 and KAT5

Pathways associated with YEATS4 recombinant protein

Products by Pathway	Pathway Diagram
Activation Of The TFAP2 (AP-2) Family Of Transcription Factors Pathway antibodies	Activation Of The TFAP2 (AP-2) Family Of Transcription Factors Pathway Diagram
C-MYB Transcription Factor Network Pathway antibodies	C-MYB Transcription Factor Network Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
HATs Acetylate Histones Pathway antibodies	HATs Acetylate Histones Pathway Diagram
Transcriptional Regulation By The AP-2 (TFAP2) Family Of Transcription Factors Pathway antibodies	Transcriptional Regulation By The AP-2 (TFAP2) Family Of Transcription Factors Pathway Diagram

Diseases associated with YEATS4 recombinant protein

Disease Name	Pubmed Publications
Liposarcoma Antibodies	>7 publications with YEATS4 and Liposarcoma
Breast Neoplasms Antibodies	>2 publications with YEATS4 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>2 publications with YEATS4 and Neoplasm Metastasis
Ovarian Neoplasms Antibodies	>1 publications with YEATS4 and Ovarian Neoplasms
Carcinoma Antibodies	>1 publications with YEATS4 and Carcinoma
Lung Neoplasms Antibodies	>1 publications with YEATS4 and Lung Neoplasms
Inflammation Antibodies	>1 publications with YEATS4 and Inflammation

Organs/Tissues associated with YEATS4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with YEATS4 and Blood
Brain Antibodies	>4 publications with YEATS4 and Brain
Embryonic Tissue Antibodies	>2 publications with YEATS4 and Embryonic Tissue
Liver Antibodies	>1 publications with YEATS4 and Liver
Lung Antibodies	>1 publications with YEATS4 and Lung
Connective Tissue Antibodies	>1 publications with YEATS4 and Connective Tissue
Mammary Gland Antibodies	>1 publications with YEATS4 and Mammary Gland
Testis Antibodies	>1 publications with YEATS4 and Testis