RAB31 Recombinant Protein

Name: RAB31 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204392
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204392

RAB31, also known as RAB22B, is a 194 amino lipid-anchored protein that localizes to the cytoplasmic side of the cell membrane and belongs to the Rasrelated GTPase superfamily. Expressed at high levels in lung, brain and heart, RAB31 may function in a similar… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB31, Recombinant Protein

Full Product Name

RAB31, 1-195aa, Human, His tag, E Coli

Product Gene Name

RAB31 recombinant protein

Product Synonym Names

RAB31 member RAS oncogene family; Rab22B

Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMMA IRELKVCLLG DTGVGKSSIV CRFVQDHFDH NISPTIGASF MTKTVPCGNE LHKFLIWDTA GQERFHSLAP MYYRGSAAAV IVYDITKQDS FYTLKKWVKE LKEHGPENIV MAIAGNKCDL SDIREVPLKD AKEYAESIGA IVVETSAKNA INIEELFQGI SRQIPPLDPH ENGNNGTIKV EKPTMQASRR CC

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

25.9 kDa (232aa), confirmed by MALDI-TOF

OMIM

U57091 mRNA

3D Structure

ModBase 3D Structure for Q13636

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RAB31 recombinant protein

Signaling pathway

Applications Tested/Suitable for RAB31 recombinant protein

SDS-PAGE

Product References and Citations for RAB31 recombinant protein

Rodriguez Gabin A G., et al. (2001) J Neurosci Res. 66:1149-1160.; Lodhi I J., et al. (2007) Cell Metab. 5: 59-72.

Other Notes

Small volumes of RAB31 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB31 purchase

MBS204392 is a recombinant protein targeting RAB31. Also known as RAB31, 1-195aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB31. It may not necessarily be applicable to this product.

NCBI GI #

33589861

NCBI GeneID

11031

NCBI Accession #

NP_006859

UniProt Primary Accession #

Q13636

UniProt Secondary Accession #

Q15770; Q9HC00; B2RBT7

UniProt Related Accession #

Q13636

GenBank Nucleotide #

NM_006868.3

NCBI Official Full Name

ras-related protein Rab-31

NCBI Official Synonym Full Names

RAB31, member RAS oncogene family

NCBI Official Symbol

RAB31

NCBI Official Synonym Symbols

Rab22B

UniProt Protein Name

Ras-related protein Rab-31

UniProt Synonym Protein Names

Ras-related protein Rab-22B

Protein Family

Ras-related protein

UniProt Gene Name

RAB31

UniProt Synonym Gene Names

RAB22B

NCBI Protein Information

ras-related protein Rab-31

NCBI Summary for RAB31

Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009]

UniProt Comments for RAB31

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Research Articles on RAB31

1. the role of Rab31 in cancer progression, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAB31 recombinant protein

Reference Product	PubMed Publications
RAB22A recombinant protein	>3 publications with RAB31 and RAB22A
OCRL recombinant protein	>1 publications with RAB31 and OCRL

Pathways associated with RAB31 recombinant protein

Products by Pathway	Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
RAB GEFs Exchange GTP For GDP On RABs Pathway antibodies	RAB GEFs Exchange GTP For GDP On RABs Pathway Diagram
RAB Geranylgeranylation Pathway antibodies	RAB Geranylgeranylation Pathway Diagram

Diseases associated with RAB31 recombinant protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>7 publications with RAB31 and Breast Neoplasms
Disease Models, Animal Antibodies	>3 publications with RAB31 and Disease Models, Animal
Neoplasm Metastasis Antibodies	>3 publications with RAB31 and Neoplasm Metastasis
Inflammation Antibodies	>2 publications with RAB31 and Inflammation
Adenocarcinoma Antibodies	>2 publications with RAB31 and Adenocarcinoma
Kidney Diseases Antibodies	>2 publications with RAB31 and Kidney Diseases
Liver Diseases Antibodies	>1 publications with RAB31 and Liver Diseases
Cell Transformation, Neoplastic Antibodies	>1 publications with RAB31 and Cell Transformation, Neoplastic
Carcinoma, Hepatocellular Antibodies	>1 publications with RAB31 and Carcinoma, Hepatocellular
Hyperplasia Antibodies	>1 publications with RAB31 and Hyperplasia

Organs/Tissues associated with RAB31 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>7 publications with RAB31 and Blood
Brain Antibodies	>5 publications with RAB31 and Brain
Skin Antibodies	>4 publications with RAB31 and Skin
Kidney Antibodies	>2 publications with RAB31 and Kidney
Eye Antibodies	>2 publications with RAB31 and Eye
Uncharacterized Tissue Antibodies	>2 publications with RAB31 and Uncharacterized Tissue
Liver Antibodies	>2 publications with RAB31 and Liver
Muscle Antibodies	>2 publications with RAB31 and Muscle
Adipose Tissue Antibodies	>2 publications with RAB31 and Adipose Tissue
Lung Antibodies	>2 publications with RAB31 and Lung