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uPK3A Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204417

uPK3A belongs to the uroplakin-3 family. uroplakins (uP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (uPII, uPIIIa, and uPIIIb) or four times (uPIa and uPIb; both belonging to the 'tetraspanin'… More details

$245 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
uPK3A, Recombinant Protein
Full Product Name
uPK3A, 19-207aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
uroplakin-3a; uPK3
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMVNLQP QLASVTFATN NPTLTTVALE KPLCMFDSKE ALTGTHEVYL YVLVDSAISR NASVQDSTNT PLGSTFLQTE GGRTGPYKAV AFDLIPCSDL PSLDAIGDVS KASQILNAYL VRVGANGTCL WDPNFQGLCN PPLSAATEYR FKYVLVNMST GLVEDQTLWS DPIRTNQLTP YSTIDTWPGR RSGG
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 2-8 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -80 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
23.1kDa (214aa), confirmed by MALDI-TOF
OMIM
AF085808 mRNA
Antigen Species
Human
Tag Information
His-tag
Domain
19-207aa

Product Categories/Family for uPK3A recombinant protein

Applications Tested/Suitable for uPK3A recombinant protein
SDS-PAGE

Product References and Citations for uPK3A recombinant protein

Shapiro, E., et al. (2000) J. urol. 164: 1048-1051.; Wu, X.R., et al. (1994) J. Biol. Chem. 269:13716-13724.

Other Notes

Small volumes of uPK3A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for uPK3A purchase

MBS204417 is a recombinant protein targeting uPK3A. Also known as uPK3A, 19-207aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for uPK3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
uroplkin 3
NCBI Official Synonym Full Names
uroplakin 3A
NCBI Official Symbol
UPK3A
NCBI Official Synonym Symbols
UP3A; UPK3; UPIII; UPIIIA
UniProt Protein Name
Uroplakin-3a
UniProt Synonym Protein Names
Uroplakin III; UPIII
Protein Family
UniProt Gene Name
UPK3A
UniProt Synonym Gene Names
UPK3; UP3a; UPIII
NCBI Protein Information
uroplakin-3a

NCBI Summary for uPK3A

This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
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UniProt Comments for uPK3A

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with uPK3A recombinant protein

Organs/Tissues associated with uPK3A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >4 publications with uPK3A and Prostate
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