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GADD45GIP1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204428

GADD45GIP1, also known as CRIF1, is a nuclear protein that plays a role in apoptosis control. This protein is expressed in a variety of tissues, including heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach. It functions as a negative… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GADD45GIP1, Recombinant Protein
Full Product Name
GADD45GIP1, 48-222aa, Human, His tag, E Coli
Product Synonym Names
Growth arrest and DNA damage-inducible proteins-interacting protein 1; CKBBP2; CRIF1; MGC4667; MGC4758; PLINP-1
Sequence
MGSSHHHHHH SSGLVPRGSH MPRWQLGPRY AAKQFARYGA ASGVVPGSLW PSPEQLRELE AEEREWYPSL ATMQESLRVK QLAEEQKRRE REQHIAECMA KMPQMIVNWQ QQQRENWEKA QADKERRARL QAEAQELLGY QVDPRSARFQ ELLQDLEKKE RKRLKEEKQK RKKEARAAAL AAAVAQDPAA SGAPSS
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 40% glycerol, 2mM DTT, 0.2M NaCl.
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
22.6 kDa (196aa), confirmed by MALDI-TOF
OMIM
AJ429498 mRNA
3D Structure
ModBase 3D Structure for Q8TAE8
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for GADD45GIP1 recombinant protein

Applications Tested/Suitable for GADD45GIP1 recombinant protein
SDS-PAGE

Product References and Citations for GADD45GIP1 recombinant protein

Chung HK., et al. (2003) J Biol Chem. 278 (30):28079-88.; Park KC., et al. (2005) Mol Endocrinol. 19 (1):12-24.

Other Notes

Small volumes of GADD45GIP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GADD45GIP1 purchase

MBS204428 is a recombinant protein targeting GADD45GIP1. Also known as GADD45GIP1, 48-222aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GADD45GIP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
growth arrest and DNA damage-inducible proteins-interacting protein 1
NCBI Official Synonym Full Names
GADD45G interacting protein 1
NCBI Official Symbol
GADD45GIP1
NCBI Official Synonym Symbols
PRG6; CRIF1; PLINP; CKBBP2; Plinp1; MRP-L59; PLINP-1; CKbetaBP2
UniProt Protein Name
Growth arrest and DNA damage-inducible proteins-interacting protein 1
UniProt Synonym Protein Names
39S ribosomal protein L59, mitochondrial; MRP-L59; CKII beta-associating protein; CR6-interacting factor 1; CRIF1; Mitochondrial large ribosomal subunit protein mL64
UniProt Gene Name
GADD45GIP1
UniProt Synonym Gene Names
MRPL59; PLINP1; PRG6; PLINP; PLINP-1
NCBI Protein Information
growth arrest and DNA damage-inducible proteins-interacting protein 1

NCBI Summary for GADD45GIP1

This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators. [provided by RefSeq, Aug 2012]

UniProt Comments for GADD45GIP1

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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