GNAZ Recombinant Protein

Name: GNAZ Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204649
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204649

Guanine nucleotide-binding protein G (z) subunit alpha, also known as GNAZ, is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This protein may play a role in maintaining the ionic balance of… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GNAZ, Recombinant Protein

Full Product Name

GNAZ, 1-355aa, Human, His tag, E Coli (Denatured)

Product Gene Name

GNAZ recombinant protein

Product Synonym Names

Guanine nucleotide-binding protein G (z) subunit alpha; G (x) alpha chain; Guanine nucleotide-binding protein G (z) subunit alpha Gz-alpha

Sequence

MGSSHHHHHH SSGLVPRGSH MGCRQSSEEK EAARRSRRID RHLRSESQRQ RREIKLLLLG TSNSGKSTIV KQMKIIHSGG FNLEACKEYK PLIIYNAIDS LTRIIRALAA LRIDFHNPDR AYDAVQLFAL TGPAESKGEI TPELLGVMRR LWADPGAQAC FSRSSEYHLE DNAAYYLNDL ERIAAADYIP TVEDILRSRD MTTGIVENKF TFKELTFKMV DVGGQRSERK KWIHCFEGVT AIIFCVELSG YDLKLYEDNQ TSRMAESLRL FDSICNNNWF INTSLILFLN KKDLLAEKIR RIPLTICFPE YKGQNTYEEA AVYIQRQFED LNRNKETKEI YSHFTCATDT SNIQFVFDAV TDVIIQNNLK YIGLC

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

43.0 kDa (375aa)

OMIM

J03260 mRNA

3D Structure

ModBase 3D Structure for P19086

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for GNAZ recombinant protein

Signal Transduction

Applications Tested/Suitable for GNAZ recombinant protein

SDS-PAGE

Application Notes for GNAZ recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for GNAZ recombinant protein

Gagnon A.W., et al. (1991) Blood. 78:1247-1253; Matsuoka M., et al. (1990) J. Biol. Chem. 265:13215-13220

Other Notes

Small volumes of GNAZ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNAZ purchase

MBS204649 is a recombinant protein targeting GNAZ. Also known as GNAZ, 1-355aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GNAZ. It may not necessarily be applicable to this product.

NCBI GI #

4504051

NCBI GeneID

2781

NCBI Accession #

NP_002064

UniProt Primary Accession #

P19086

UniProt Secondary Accession #

Q4QRJ6; B2R6C1

UniProt Related Accession #

P19086

GenBank Nucleotide #

NM_002073.3

NCBI Official Full Name

guanine nucleotide-binding protein G(z) subunit alpha

NCBI Official Synonym Full Names

G protein subunit alpha z

NCBI Official Symbol

GNAZ

NCBI Official Synonym Symbols

gz-alpha

UniProt Protein Name

Guanine nucleotide-binding protein G(z) subunit alpha

UniProt Synonym Protein Names

G(x) alpha chain; Gz-alpha

UniProt Gene Name

GNAZ

NCBI Protein Information

guanine nucleotide-binding protein G(z) subunit alpha

NCBI Summary for GNAZ

The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]

UniProt Comments for GNAZ

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Research Articles on GNAZ

1. GNAZ mutations are associated with melanoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GNAZ recombinant protein

Reference Product	PubMed Publications
RGS20 recombinant protein	>4 publications with GNAZ and RGS20
RGS4 recombinant protein	>2 publications with GNAZ and RGS4
GNB1 recombinant protein	>1 publications with GNAZ and GNB1
GNB2 recombinant protein	>1 publications with GNAZ and GNB2

Pathways associated with GNAZ recombinant protein

Products by Pathway	Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Chaperonin-mediated Protein Folding Pathway antibodies	Chaperonin-mediated Protein Folding Pathway Diagram
Cooperation Of PDCL (PhLP1) And TRiC/CCT In G-protein Beta Folding Pathway antibodies	Cooperation Of PDCL (PhLP1) And TRiC/CCT In G-protein Beta Folding Pathway Diagram
Corticotropin-releasing Hormone Signaling Pathway antibodies	Corticotropin-releasing Hormone Signaling Pathway Diagram
G Protein Signaling Pathways antibodies	G Protein Signaling Pathways Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
G Alpha (z) Signalling Events Pathway antibodies	G Alpha (z) Signalling Events Pathway Diagram
G-protein Activation Pathway antibodies	G-protein Activation Pathway Diagram
G-protein Mediated Events Pathway antibodies	G-protein Mediated Events Pathway Diagram

Diseases associated with GNAZ recombinant protein

Disease Name	Pubmed Publications
Liver Neoplasms Antibodies	>2 publications with GNAZ and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with GNAZ and Liver Diseases
Necrosis Antibodies	>2 publications with GNAZ and Necrosis
Cell Transformation, Neoplastic Antibodies	>1 publications with GNAZ and Cell Transformation, Neoplastic
Fibrosis Antibodies	>1 publications with GNAZ and Fibrosis
Inflammation Antibodies	>1 publications with GNAZ and Inflammation

Organs/Tissues associated with GNAZ recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>26 publications with GNAZ and Brain
Nerve Antibodies	>7 publications with GNAZ and Nerve
Kidney Antibodies	>5 publications with GNAZ and Kidney
Ganglia Antibodies	>3 publications with GNAZ and Ganglia
Pancreas Antibodies	>3 publications with GNAZ and Pancreas
Eye Antibodies	>3 publications with GNAZ and Eye
Lung Antibodies	>2 publications with GNAZ and Lung
Liver Antibodies	>2 publications with GNAZ and Liver
Bone Antibodies	>1 publications with GNAZ and Bone