PTPN7 Recombinant Protein

Name: PTPN7 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204655
Price: 365 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204655

PTPN7, also known as tyrosine-protein phosphatase non-receptor type 7 isoform 1, acts preferentially on tyrosine-phosphorylated MAPK1. This protein plays a role in the regulation of T and B-lymphocyte development and signal transduction. Recombinant human… More details

$365 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTPN7, Recombinant Protein

Full Product Name

PTPN7, 1-360aa, Human, His tag, E Coli

Product Gene Name

PTPN7 recombinant protein

Product Synonym Names

Tyrosine-protein phosphatase non-receptor type 7; Tyrosine-protein phosphatase non-receptor type 7; BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI

Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

43.1 kDa (384aa), confirmed by MALDI-TOF

OMIM

D11327 mRNA

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for PTPN7 recombinant protein

Enzymes & Proteases

Applications Tested/Suitable for PTPN7 recombinant protein

SDS-PAGE

Product References and Citations for PTPN7 recombinant protein

Pettiford S.M., et al. (2000) Oncogene. 19:858-869; Nika K., et al. (2004) Biochem. J. 378:335-342;

Other Notes

Small volumes of PTPN7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPN7 purchase

MBS204655 is a recombinant protein targeting PTPN7. Also known as PTPN7, 1-360aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN7. It may not necessarily be applicable to this product.

NCBI GI #

18375658

NCBI GeneID

5778

NCBI Accession #

NP_002823.2

UniProt Secondary Accession #

Q53XK4; Q5SXQ0; Q5SXQ1; Q9BV05; B3KXE1

UniProt Related Accession #

P35236

GenBank Nucleotide #

NM_002832.2

NCBI Official Full Name

tyrosine-protein phosphatase non-receptor type 7 isoform 1

NCBI Official Synonym Full Names

protein tyrosine phosphatase, non-receptor type 7

NCBI Official Symbol

PTPN7

NCBI Official Synonym Symbols

LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP

UniProt Protein Name

Tyrosine-protein phosphatase non-receptor type 7

UniProt Synonym Protein Names

Hematopoietic protein-tyrosine phosphatase; HEPTP; Protein-tyrosine phosphatase LC-PTP

Protein Family

Tyrosine-protein phosphatase non-receptor

UniProt Gene Name

PTPN7

UniProt Synonym Gene Names

HEPTP

NCBI Protein Information

tyrosine-protein phosphatase non-receptor type 7

NCBI Summary for PTPN7

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for PTPN7

Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.

Research Articles on PTPN7

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTPN7 recombinant protein

Reference Product	PubMed Publications
PTPRR recombinant protein	>4 publications with PTPN7 and PTPRR
MAPK14 recombinant protein	>3 publications with PTPN7 and MAPK14
DUSP3 recombinant protein	>1 publications with PTPN7 and DUSP3
MAPK1 recombinant protein	>1 publications with PTPN7 and MAPK1

Pathways associated with PTPN7 recombinant protein

Products by Pathway	Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Ras Signaling In The CD4+ TCR Pathway antibodies	Ras Signaling In The CD4+ TCR Pathway Diagram

Diseases associated with PTPN7 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with PTPN7 and Inflammation
Necrosis Antibodies	>2 publications with PTPN7 and Necrosis
Death Antibodies	>1 publications with PTPN7 and Death
Diabetes Mellitus, Type 2 Antibodies	>1 publications with PTPN7 and Diabetes Mellitus, Type 2
Diabetes Mellitus Antibodies	>1 publications with PTPN7 and Diabetes Mellitus
Weight Loss Antibodies	>1 publications with PTPN7 and Weight Loss

Organs/Tissues associated with PTPN7 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>11 publications with PTPN7 and Blood
Brain Antibodies	>2 publications with PTPN7 and Brain
Stomach Antibodies	>1 publications with PTPN7 and Stomach
Lung Antibodies	>1 publications with PTPN7 and Lung
Kidney Antibodies	>1 publications with PTPN7 and Kidney