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NDuFS6 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205102

NDuFS6 is a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit is… More details

$230 / 0.02 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
NDuFS6, Recombinant Protein
Full Product Name
NDuFS6, 28-124aa, Human, His tag, E Coli
Product Synonym Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6; CI-13Ka; CI-13kD-A; CI13KDA
Sequence
MGSSHHHHHH SSGLVPRGSH MGSFGVRVSP TGEKVTHTGQ VYDDKDYRRI RFVGRQKEVN ENFAIDLIAE QPVSEVETRV IACDGGGGAL GHPKVYINLD KETKTGTCGY CGLQFRQHHH
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
13.2kDa (120aa), confirmed by MALDI-TOF
OMIM
AF044959 mRNA
3D Structure
ModBase 3D Structure for O75380
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for NDuFS6 recombinant protein

Applications Tested/Suitable for NDuFS6 recombinant protein
SDS-PAGE

Product References and Citations for NDuFS6 recombinant protein

Hendrickson,S.L., et al. (2010) PLoS ONE 5 (9), E12862; Saito,A., et al. (2009) J. Hum. Genet. 54 (6), 317-323

Other Notes

Small volumes of NDuFS6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NDuFS6 purchase

MBS205102 is a recombinant protein targeting NDuFS6. Also known as NDuFS6, 28-124aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NDuFS6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH:ubiquinone oxidoreductase subunit S6
NCBI Official Symbol
NDUFS6
NCBI Official Synonym Symbols
CI-13kA; CI13KDA; CI-13kD-A
UniProt Protein Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
UniProt Synonym Protein Names
Complex I-13kD-A; CI-13kD-A; NADH-ubiquinone oxidoreductase 13 kDa-A subunit
UniProt Gene Name
NDUFS6
UniProt Synonym Gene Names
CI-13kD-A
NCBI Protein Information
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

NCBI Summary for NDuFS6

This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]
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UniProt Comments for NDuFS6

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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