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TBC1D1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205148

TBC1 (tre-2/uSP6, BuB2, cdc16) domain family, member 1, also known as TBC1D1, may act as a GTPase-activating protein for Rab family protein (s). This protein may play a role in the cell cycle and differentiation of various tissues. This protein is involved in… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBC1D1, Recombinant Protein
Full Product Name
TBC1D1, 1-265aa, Human, His tag, E Coli (Denatured)
Product Synonym Names
TBC1 (tre-2/uSP6 BuB2 cdc16) domain family member 1; TBC1 (tre-2/uSP6; BuB2; cdc16) domain family; member 1; TBC; TBC1
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD
Host
E Coli
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
Purity/Purification
> 90% by SDS-PAGE
Concentration
1mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
33.2 kDa (288aa)
OMIM
AK027355 mRNA
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for TBC1D1 recombinant protein

Applications Tested/Suitable for TBC1D1 recombinant protein
SDS-PAGE
Application Notes for TBC1D1 recombinant protein
This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for TBC1D1 recombinant protein

Stone S., et al. (2006) Hum. Mol. Genet. 15:2709-2720; Meyre D., et al. (2008) Hum. Mol. Genet. 17:1798-1802;

Other Notes

Small volumes of TBC1D1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBC1D1 purchase

MBS205148 is a recombinant protein targeting TBC1D1. Also known as TBC1D1, 1-265aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TBC1 domain family member 1 isoform 3
NCBI Official Synonym Full Names
TBC1 domain family member 1
NCBI Official Symbol
TBC1D1
NCBI Official Synonym Symbols
TBC; TBC1
UniProt Protein Name
TBC1 domain family member 1
Protein Family
UniProt Gene Name
TBC1D1
UniProt Synonym Gene Names
KIAA1108
NCBI Protein Information
TBC1 domain family member 1

NCBI Summary for TBC1D1

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008]
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UniProt Comments for TBC1D1

May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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