ZC4H2 Recombinant Protein

Name: ZC4H2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205162
Price: 375 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205162

ZC4H2 is a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. ZC4H2 has been… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ZC4H2, Recombinant Protein

Full Product Name

ZC4H2, 1-224aa, Human, His tag, E Coli

Product Gene Name

ZC4H2 recombinant protein

Product Synonym Names

Zinc finger C4H2 domain-containing protein isoform 1; Zinc finger; C4H2 domain containing; HCA127; KIAA1166

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMADEQEI MCKLESIKEI RNKTLQMEKI KARLKAEFEA LESEERHLKE YKQEMDLLLQ EKMAHVEELR LIHADINVME NTIKQSENDL NKLLESTRRL HDEYKPLKEH VDALRMTLGL QRLPDLCEEE EKLSLDYFEK QKAEWQTEPQ EPPIPESLAA AAAAAQQLQV ARKQDTRQTA TFRQQPPPMK ACLSCHQQIH RNAPICPLCK AKSRSRNPKK PKRKQDE

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl (pH 8.5) containing 50% glycerol, 0.2M NaCl, 2mM DTT

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.25mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

28.6 kDa (247aa) confirmed by MALDI-TOF

OMIM

AF270491 mRNA

3D Structure

ModBase 3D Structure for Q9NQZ6

Antigen Species

Human

Tag Information

His-tag

Applications Tested/Suitable for ZC4H2 recombinant protein

SDS-PAGE

Product References and Citations for ZC4H2 recombinant protein

Wang Y., Han K.-J. et al. (2002), J. Immunol. 169:1102-1109

Other Notes

Small volumes of ZC4H2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZC4H2 purchase

MBS205162 is a recombinant protein targeting ZC4H2. Also known as ZC4H2, 1-224aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ZC4H2. It may not necessarily be applicable to this product.

NCBI GI #

8923720

NCBI GeneID

55906

NCBI Accession #

NP_061154

UniProt Primary Accession #

Q9NQZ6

UniProt Secondary Accession #

Q53H73; Q5JTF9; Q9H9C3; Q9H9H7; Q9ULQ4; B2RDC2; B3KVZ5; B4DED0; E7EM74; G3V1L3

UniProt Related Accession #

Q9NQZ6

GenBank Nucleotide #

NM_018684.3

NCBI Official Full Name

zinc finger C4H2 domain-containing protein isoform 1

NCBI Official Synonym Full Names

zinc finger C4H2-type containing

NCBI Official Symbol

ZC4H2

NCBI Official Synonym Symbols

WWS; WRWF; HCA127; KIAA1166

UniProt Protein Name

Zinc finger C4H2 domain-containing protein

UniProt Synonym Protein Names

Hepatocellular carcinoma-associated antigen 127

Protein Family

Zinc finger C4H2 domain-containing protein

UniProt Gene Name

ZC4H2

UniProt Synonym Gene Names

HCA127; KIAA1166

NCBI Protein Information

zinc finger C4H2 domain-containing protein

NCBI Summary for ZC4H2

This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

UniProt Comments for ZC4H2

Plays a role in interneurons differentiation (PubMed:26056227). Involved in neuronal development and in neuromuscular junction formation.

Research Articles on ZC4H2

1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ZC4H2 recombinant protein

Disease Name	Pubmed Publications
Neurobehavioral Manifestations Antibodies	>3 publications with ZC4H2 and Neurobehavioral Manifestations
Atrophy Antibodies	>3 publications with ZC4H2 and Atrophy
Chromosome Breakage Antibodies	>1 publications with ZC4H2 and Chromosome Breakage
Musculoskeletal Abnormalities Antibodies	>1 publications with ZC4H2 and Musculoskeletal Abnormalities
Miles-Carpenter x-linked mental retardation syndrome Antibodies	>1 publications with ZC4H2 and Miles-Carpenter x-linked mental retardation syndrome
Microcephaly Antibodies	>1 publications with ZC4H2 and Microcephaly

Organs/Tissues associated with ZC4H2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with ZC4H2 and Brain
Muscle Antibodies	>2 publications with ZC4H2 and Muscle
Bone Antibodies	>1 publications with ZC4H2 and Bone
Eye Antibodies	>1 publications with ZC4H2 and Eye