• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

HN1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205217

Hematological and neurological expressed 1 protein, also known as HN1, is a small protein that is highly conserved among species. HN1 expression is upregulated in regenerating neural tissues, including the axotomized adult rodent facial motor nerve and… More details

$265 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HN1, Recombinant Protein
Full Product Name
HN1, 1-154aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Hematological and neurological expressed 1 protein; ARM2; HN1A
Sequence
MGSSHHHHHH SSGLVPRGSH MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.5 mg/ml (determined by BCA assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
18.1kDa (174aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
3D Structure
ModBase 3D Structure for Q9UK76
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for HN1 recombinant protein

Applications Tested/Suitable for HN1 recombinant protein
SDS-PAGE

Product References and Citations for HN1 recombinant protein

Laughlin K M., et al. (2009) Differentiation. 78 (1):35-44; Zhou G., et al. (2004) Gene. 331:115-23.;

Other Notes

Small volumes of HN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HN1 purchase

MBS205217 is a recombinant protein targeting HN1. Also known as HN1, 1-154aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
jupiter microtubule associated homolog 1 isoform 1
NCBI Official Synonym Full Names
Jupiter microtubule associated homolog 1
NCBI Official Symbol
JPT1
NCBI Official Synonym Symbols
HN1; ARM2; HN1A
UniProt Protein Name
Jupiter microtubule associated homolog 1
UniProt Synonym Protein Names
Androgen-regulated protein 2; Hematological and neurological expressed 1 protein
UniProt Gene Name
JPT1
NCBI Protein Information
jupiter microtubule associated homolog 1

UniProt Comments for HN1

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HN1 recombinant protein

Diseases associated with HN1 recombinant protein

Organs/Tissues associated with HN1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with HN1 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000