TAC1 Recombinant Protein

Name: TAC1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205274
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205274

TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAC1, Recombinant Protein

Full Product Name

TAC1, 20-129aa, Human, His tag, E Coli (Denatured)

Product Gene Name

TAC1 recombinant protein

Product Synonym Names

Protachykinin-1; Protachykinin 1; 4930528L02Rik; NK-1; NK1; Nka; Nkna; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide K; Substance P; Tachykinin precursor 1

Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMEEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALL KALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 2M urea

Purity/Purification

> 95% by SDS-PAGE

Concentration

1.0 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

15.6 kDa (135aa)

OMIM

X54469 mRNA

3D Structure

ModBase 3D Structure for P20366

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for TAC1 recombinant protein

Neuroscience

Applications Tested/Suitable for TAC1 recombinant protein

SDS-PAGE

Application Notes for TAC1 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for TAC1 recombinant protein

Advenier C. et al. (1997) Eur Respir J. 10:1892-1906.; Bannon MJ. et al. (1992) Brain Res Mol Brain Res. 12:225-231.;

Other Notes

Small volumes of TAC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAC1 purchase

MBS205274 is a recombinant protein targeting TAC1. Also known as TAC1, 20-129aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TAC1. It may not necessarily be applicable to this product.

NCBI GI #

4507341

NCBI GeneID

6863

NCBI Accession #

NP_003173

UniProt Primary Accession #

P20366

UniProt Secondary Accession #

O60600; O60601; Q00072; Q53GH4; Q549V0; Q549V1; Q549V2; Q6FHM1

UniProt Related Accession #

P20366

GenBank Nucleotide #

NM_003182.2

NCBI Official Full Name

protachykinin-1 isoform beta

NCBI Official Synonym Full Names

tachykinin precursor 1

NCBI Official Symbol

TAC1

NCBI Official Synonym Symbols

NK2; NPK; NKNA; TAC2; Hs.2563

UniProt Protein Name

Protachykinin-1

UniProt Synonym Protein Names

PPT

Protein Family

Protachykinin

UniProt Gene Name

TAC1

UniProt Synonym Gene Names

NKA; NKNA; TAC2; NKA; NPK

NCBI Protein Information

protachykinin-1

NCBI Summary for TAC1

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

UniProt Comments for TAC1

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Research Articles on TAC1

1. Data suggest that serum substance P concentrations at the day of oocyte retrieval after ovulation induction may be used to predict oocyte maturation during in vitro oocyte maturation to be followed by intracytoplasmic sperm injections and may be an indirect indicator for treatment outcome in women with infertility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TAC1 recombinant protein

Reference Product	PubMed Publications
TACR1 recombinant protein	>17 publications with TAC1 and TACR1
TAC3 recombinant protein	>11 publications with TAC1 and TAC3
TACR2 recombinant protein	>8 publications with TAC1 and TACR2
TACR3 recombinant protein	>6 publications with TAC1 and TACR3
NTS recombinant protein	>4 publications with TAC1 and NTS
CCK recombinant protein	>1 publications with TAC1 and CCK
NPS recombinant protein	>1 publications with TAC1 and NPS

Pathways associated with TAC1 recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways antibodies	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways Diagram
Tachykinin Receptors Bind Tachykinins Pathway antibodies	Tachykinin Receptors Bind Tachykinins Pathway Diagram

Diseases associated with TAC1 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>26 publications with TAC1 and Inflammation
Pain Antibodies	>25 publications with TAC1 and Pain
Nervous System Diseases Antibodies	>23 publications with TAC1 and Nervous System Diseases
Disease Models, Animal Antibodies	>16 publications with TAC1 and Disease Models, Animal
Hyperalgesia Antibodies	>9 publications with TAC1 and Hyperalgesia
Necrosis Antibodies	>6 publications with TAC1 and Necrosis
Neurogenic Inflammation Antibodies	>5 publications with TAC1 and Neurogenic Inflammation
Schizophrenia Antibodies	>5 publications with TAC1 and Schizophrenia
Bipolar Disorder Antibodies	>5 publications with TAC1 and Bipolar Disorder
Hypertension Antibodies	>5 publications with TAC1 and Hypertension

Organs/Tissues associated with TAC1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>50 publications with TAC1 and Brain
Nerve Antibodies	>21 publications with TAC1 and Nerve
Embryonic Tissue Antibodies	>4 publications with TAC1 and Embryonic Tissue
Eye Antibodies	>3 publications with TAC1 and Eye
Connective Tissue Antibodies	>2 publications with TAC1 and Connective Tissue
Kidney Antibodies	>2 publications with TAC1 and Kidney
Uncharacterized Tissue Antibodies	>1 publications with TAC1 and Uncharacterized Tissue
Placenta Antibodies	>1 publications with TAC1 and Placenta
Spleen Antibodies	>1 publications with TAC1 and Spleen