Rabbit Anti-KRT18 Polyclonal Antibody – Cat# MBS2052863

Knockout Validation: Lane 1: Wild-type Hela cell lysate;;Lane 2: KRT18 knockout Hela cell lysate;;Predicted MW: 48kDa ;Observed MW: 48kDa;Primary Ab: 2ug/ml Rabbit Anti-Human KRT18 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047)

Keratin 18 (KRT18) Antibody – Rabbit Polyclonal

Name: KRT18 Antibody; Polyclonal; Rabbit; Human/Rat/Pig-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2052863
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2052863

MBS2052863 is an antibody targeting KRT18. Also known as APC/CY7-Linked Polyclonal Antibody to Keratin 18 (KRT18). Reactive in Human, Rat, Pig. Host: Rabbit. More details

$430 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Keratin 18 (KRT18), Polyclonal Antibody

Full Product Name

APC/CY7-Linked Polyclonal Antibody to Keratin 18 (KRT18)

Product Gene Name

anti-KRT18 antibody

Product Synonym Names

CK18; CYK18; K18; Cytokeratin 18; Cell proliferation-inducing gene 46 protein; Keratin, type I cytoskeletal 18

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Rat, Pig

Concentration

>=100ug/ml (lot specific)

Matching Pairs

Unconjugated Antibody: KRT18 (MBS2003165)
APC-CY7 Conjugated Antibody: KRT18 (MBS2052863)

Matching Pairs

APC-CY7 Conjugated Antibody: KRT18 (MBS2052863)
Immunogen: KRT18 (MBS2011934)

Molecular Weight

48,058 Da

OMIM

X12881 mRNA

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Immunogen

KRT18 (Asp238~Leu396)

Conjugation

APC-Cy7

Cross Reactivity

Human, Pig

Unconjugated Antibody

The unconjugated antibody version of this item is also available as catalog #MBS2003165

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-KRT18 antibody

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-KRT18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT18. It may not necessarily be applicable to this product.

NCBI GI #

386844

NCBI Accession #

AAA59461.1

UniProt Secondary Accession #

Q53G38; Q5U0N8; Q9BW26

NCBI Official Full Name

keratin 18

UniProt Protein Name

Keratin, type I cytoskeletal 18

UniProt Synonym Protein Names

Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18

Protein Family

Keratin

UniProt Gene Name

KRT18

UniProt Synonym Gene Names

CYK18; CK-18; K18

UniProt Comments for KRT18

K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.

Protein type: Cytoskeletal; Nucleolus

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cell-cell adherens junction; cytoplasm; intermediate filament; keratin filament; microtubule organizing center

Molecular Function: protein binding

Biological Process: anatomical structure morphogenesis; Golgi to plasma membrane CFTR protein transport; intermediate filament cytoskeleton organization and biogenesis; negative regulation of apoptosis

Disease: Cirrhosis, Familial

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT18 antibody

Reference Product	PubMed Publications
KRT8 antibody	>42 publications with KRT18 and KRT8
TCHP antibody	>1 publications with KRT18 and TCHP
CASP6 antibody	>1 publications with KRT18 and CASP6

Pathways associated with anti-KRT18 antibody

Products by Pathway	Pathway Diagram
Caspase Cascade In Apoptosis Pathway antibodies	Caspase Cascade In Apoptosis Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram
Pathogenic Escherichia Coli Infection Pathway antibodies	Pathogenic Escherichia Coli Infection Pathway Diagram
Pathogenic Escherichia Coli Infection Pathway antibodies	Pathogenic Escherichia Coli Infection Pathway Diagram
Pathogenic Escherichia Coli Infection Pathway antibodies	Pathogenic Escherichia Coli Infection Pathway Diagram

Diseases associated with anti-KRT18 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>46 publications with KRT18 and Neoplasms
Liver Diseases Antibodies	>29 publications with KRT18 and Liver Diseases
Carcinoma Antibodies	>26 publications with KRT18 and Carcinoma
Skin Diseases Antibodies	>18 publications with KRT18 and Skin Diseases
Breast Neoplasms Antibodies	>15 publications with KRT18 and Breast Neoplasms
Adenocarcinoma Antibodies	>14 publications with KRT18 and Adenocarcinoma
Fibrosis Antibodies	>12 publications with KRT18 and Fibrosis
Neoplasm Metastasis Antibodies	>11 publications with KRT18 and Neoplasm Metastasis
Fatty Liver Antibodies	>10 publications with KRT18 and Fatty Liver
Liver Cirrhosis Antibodies	>8 publications with KRT18 and Liver Cirrhosis

Organs/Tissues associated with anti-KRT18 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>35 publications with KRT18 and Liver
Blood Antibodies	>19 publications with KRT18 and Blood
Eye Antibodies	>6 publications with KRT18 and Eye
Muscle Antibodies	>6 publications with KRT18 and Muscle
Lymph Antibodies	>6 publications with KRT18 and Lymph
Lymph Node Antibodies	>6 publications with KRT18 and Lymph Node
Kidney Antibodies	>6 publications with KRT18 and Kidney
Prostate Antibodies	>5 publications with KRT18 and Prostate
Stomach Antibodies	>5 publications with KRT18 and Stomach
Mammary Gland Antibodies	>4 publications with KRT18 and Mammary Gland