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PRRX1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205374

Paired related homeobox 1, also known as PRRX1, acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRRX1, Recombinant Protein
Full Product Name
PRRX1, 1-217aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Paired related homeobox 1; AGOTC; PHOX1; PMX1; PRX-1; PRX1
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Purity/Purification
> 85% by SDS-PAGE
Concentration
0.25mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
26.9 kDa (241aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
OMIM
AB451463 mRNA
3D Structure
ModBase 3D Structure for P54821
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for PRRX1 recombinant protein

Applications Tested/Suitable for PRRX1 recombinant protein
SDS-PAGE

Product References and Citations for PRRX1 recombinant protein

Grueneberg D.A., et al. (1992) Science. 257:1089-1095; Sergi C., et al. (2011) Clin. Genet. 79:293-295;

Other Notes

Small volumes of PRRX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRRX1 purchase

MBS205374 is a recombinant protein targeting PRRX1. Also known as PRRX1, 1-217aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PRRX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
paired mesoderm homeobox protein 1 isoform pmx-1a
NCBI Official Synonym Full Names
paired related homeobox 1
NCBI Official Symbol
PRRX1
NCBI Official Synonym Symbols
PMX1; PRX1; AGOTC; PHOX1; PRX-1
UniProt Protein Name
Paired mesoderm homeobox protein 1
UniProt Synonym Protein Names
Homeobox protein PHOX1; Paired-related homeobox protein 1; PRX-1
UniProt Gene Name
PRRX1
UniProt Synonym Gene Names
PMX1; PRX-1
NCBI Protein Information
paired mesoderm homeobox protein 1

NCBI Summary for PRRX1

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]
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UniProt Comments for PRRX1

Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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