SuLT1C4 Recombinant Protein

Name: SuLT1C4 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205387
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205387

Sulfotransferase 1C4, also known as SuLT1C4, belongs to the SuLT subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters,… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SuLT1C4, Recombinant Protein

Full Product Name

SuLT1C4 1-302aa, Human, His tag, E Coli

Product Gene Name

SuLT1C4 recombinant protein

Product Synonym Names

Sulfotransferase 1C4; SuLT1C; SuLT1C2

Sequence

MGSSHHHHHH SSGLVPRGSH MALHDMEDFT FDGTKRLSVN YVKGILQPTD TCDIWDKIWN FQAKPDDLLI STYPKAGTTW TQEIVELIQN EGDVEKSKRA PTHQRFPFLE MKIPSLGSGL EQAHAMPSPR ILKTHLPFHL LPPSLLEKNC KIIYVARNPK DNMVSYYHFQ RMNKALPAPG TWEEYFETFL AGKVCWGSWH EHVKGWWEAK DKHRILYLFY EDMKKNPKHE IQKLAEFIGK KLDDKVLDKI VHYTSFDVMK QNPMANYSSI PAEIMDHSIS PFMRKGAVGD WKKHFTVAQN ERFDEDYKKK MTDTRLTFHF QF

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Purity/Purification

> 95% by SDS-PAGE

Concentration

1mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

37.6kDa (322aa), confirmed by MALDI-TOF

OMIM

AF055584 mRNA

3D Structure

ModBase 3D Structure for O75897

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for SuLT1C4 recombinant protein

Metabolism

Applications Tested/Suitable for SuLT1C4 recombinant protein

SDS-PAGE

Product References and Citations for SuLT1C4 recombinant protein

Sakakibara Y., et al. (1998) J Biol Chem. 273 (51):33929-35

Other Notes

Small volumes of SuLT1C4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SuLT1C4 purchase

MBS205387 is a recombinant protein targeting SuLT1C4. Also known as SuLT1C4 1-302aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SuLT1C4. It may not necessarily be applicable to this product.

NCBI GI #

28830308

NCBI GeneID

27233

NCBI Accession #

NP_006579

UniProt Primary Accession #

O75897

UniProt Secondary Accession #

Q069I8; Q08AS5; Q53S63

UniProt Related Accession #

O75897

GenBank Nucleotide #

NM_006588.3

NCBI Official Full Name

sulfotransferase 1C4 isoform 1

NCBI Official Synonym Full Names

sulfotransferase family 1C member 4

NCBI Official Symbol

SULT1C4

NCBI Official Synonym Symbols

SULT1C; SULT1C2

UniProt Protein Name

Sulfotransferase 1C4

UniProt Synonym Protein Names

Sulfotransferase 1C2; SULT1C#2

Protein Family

Sulfotransferase

UniProt Gene Name

SULT1C4

UniProt Synonym Gene Names

SULT1C2; ST1C4; SULT1C#2

NCBI Protein Information

sulfotransferase 1C4

NCBI Summary for SuLT1C4

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008]

UniProt Comments for SuLT1C4

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hydroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).

Research Articles on SuLT1C4

1. The current study aimed to identify the human cytosolic sulfotransferase(s) that is(are) capable of sulfating doxorubicin and its analog epirubicin, and to verify whether sulfation of doxorubicin and epirubicin may occur under metabolic conditions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SuLT1C4 recombinant protein

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Cytosolic Sulfonation Of Small Molecules Pathway antibodies	Cytosolic Sulfonation Of Small Molecules Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metapathway Biotransformation antibodies	Metapathway Biotransformation Diagram
Phase II Conjugation Pathway antibodies	Phase II Conjugation Pathway Diagram
Sulfation Biotransformation Reaction Pathway antibodies	Sulfation Biotransformation Reaction Pathway Diagram

Diseases associated with SuLT1C4 recombinant protein

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>4 publications with SuLT1C4 and Adenocarcinoma
Fatty Liver Antibodies	>2 publications with SuLT1C4 and Fatty Liver
Lung Neoplasms Antibodies	>1 publications with SuLT1C4 and Lung Neoplasms
Non-alcoholic Fatty Liver Disease Antibodies	>1 publications with SuLT1C4 and Non-alcoholic Fatty Liver Disease
Carcinoma, Hepatocellular Antibodies	>1 publications with SuLT1C4 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with SuLT1C4 and Liver Neoplasms
Kidney Diseases Antibodies	>1 publications with SuLT1C4 and Kidney Diseases

Organs/Tissues associated with SuLT1C4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>11 publications with SuLT1C4 and Lung
Kidney Antibodies	>11 publications with SuLT1C4 and Kidney