CGB Recombinant Protein

Name: CGB Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205434
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205434

CGB is a member of the glycoprotein hormone beta chain family and is the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CGB, Recombinant Protein

Full Product Name

CGB, 21-165aa, Human, His tag, E Coli (Denatured)

Product Gene Name

CGB recombinant protein

Product Synonym Names

Choriogonadotropin subunit beta precursor; CGB3; CGB5; CGB7; CGB8; Hcgb

Sequence

MGSSHHHHHH SSGLVPRGSH MGSSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

17.9 kDa (168aa)

OMIM

J00117 mRNA

3D Structure

ModBase 3D Structure for P0DN86

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for CGB recombinant protein

Hormones & Cytokines

Applications Tested/Suitable for CGB recombinant protein

SDS-PAGE

Application Notes for CGB recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for CGB recombinant protein

Andrusiewicz M, Szczerba A, et al. (2011). J Transl Med. 9:130.; Gregor CR, Cerasoli E, et al. (2011). J Biol Chem. 286 (28):25016-26. ;

Other Notes

Small volumes of CGB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CGB purchase

MBS205434 is a recombinant protein targeting CGB. Also known as CGB, 21-165aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CGB. It may not necessarily be applicable to this product.

NCBI GI #

4502789

NCBI GeneID

1082

NCBI Accession #

NP_000728

UniProt Primary Accession #

P0DN86

UniProt Secondary Accession #

P01233; Q13991; Q14000; Q3KPI3; Q3SY41; Q8WTT5; Q8WXL1; Q8WXL2; Q8WXL3; A1A5E0; B9ZVP5

UniProt Related Accession #

P0DN86

GenBank Nucleotide #

NM_000737.3

NCBI Official Full Name

choriogonadotropin subunit beta 3

NCBI Official Synonym Full Names

chorionic gonadotropin beta subunit 3

NCBI Official Symbol

CGB3

NCBI Official Synonym Symbols

CGB; CGB5; CGB7; CGB8; hCGB

UniProt Protein Name

Choriogonadotropin subunit beta 3

UniProt Synonym Protein Names

Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta

Protein Family

Choriogonadotropin

UniProt Gene Name

CGB3

UniProt Synonym Gene Names

CGB; CG-beta

NCBI Protein Information

choriogonadotropin subunit beta 3

NCBI Summary for CGB

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

UniProt Comments for CGB

Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Research Articles on CGB

1. the results of this study provide novel evidence supporting a role of hCG in regulating the differentiation of peripheral FOXP3(+) Tregs, which affect the pregnancy outcomes of patients with a history of recurrent implantation failure

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CGB recombinant protein

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
Glycoprotein Hormones Pathway antibodies	Glycoprotein Hormones Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Biosynthesis Pathway antibodies	Peptide Hormone Biosynthesis Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
TFAP2 (AP-2) Family Regulates Transcription Of Growth Factors And Their Receptors Pathway antibodies	TFAP2 (AP-2) Family Regulates Transcription Of Growth Factors And Their Receptors Pathway Diagram
Transcriptional Regulation By The AP-2 (TFAP2) Family Of Transcription Factors Pathway antibodies	Transcriptional Regulation By The AP-2 (TFAP2) Family Of Transcription Factors Pathway Diagram

Organs/Tissues associated with CGB recombinant protein

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>3 publications with CGB and Placenta
Embryonic Tissue Antibodies	>2 publications with CGB and Embryonic Tissue