NTS Recombinant Protein

Name: NTS Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205472
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205472

Neurotensin, also known as NTS, is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NTS, Recombinant Protein

Full Product Name

NTS, 24-170aa, Human, His tag, E Coli (Denatured)

Product Gene Name

NTS recombinant protein

Product Synonym Names

Neurotensin neuromedin N; Neurotensin; neuromedin N; NMN-125; NN; NT; NT/N; NTS1

Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSDSEE EMKALEADFL TNMHTSKISK AHVPSWKMTL LNVCSLVNNL NSPAEETGEV HEEELVARRK LPTALDGFSL EAMLTIYQLH KICHSRAFQH WELIQEDILD TGNDKNGKEE VIKRKIPYIL KRQLYENKPR RPYILKRDSY YY

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

19.9 kDa (172aa)

OMIM

U91618 mRNA

3D Structure

ModBase 3D Structure for P30990

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for NTS recombinant protein

Metabolism

Applications Tested/Suitable for NTS recombinant protein

SDS-PAGE

Application Notes for NTS recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for NTS recombinant protein

Bean A.J., et al. (1992) Neuroscience. 50:259-268; Quistgaard E.M., et al. (2009) Nat. Struct. Mol. Biol. 16:96-98;

Other Notes

Small volumes of NTS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NTS purchase

MBS205472 is a recombinant protein targeting NTS. Also known as NTS, 24-170aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NTS. It may not necessarily be applicable to this product.

NCBI GI #

5453816

NCBI GeneID

4922

NCBI Accession #

NP_006174

UniProt Primary Accession #

P30990

UniProt Related Accession #

P30990

GenBank Nucleotide #

NM_006183.4

NCBI Official Full Name

neurotensin/neuromedin N preproprotein

NCBI Official Synonym Full Names

neurotensin

NCBI Official Symbol

NTS

NCBI Official Synonym Symbols

NN; NT; NT/N; NTS1; NMN-125

UniProt Protein Name

Neurotensin/neuromedin N

UniProt Synonym Protein Names

Large neuromedin NAlternative name(s):NmN-125

Protein Family

Neurotensin

UniProt Gene Name

NTS

UniProt Synonym Gene Names

NN; NmN; NT

NCBI Protein Information

neurotensin/neuromedin N

NCBI Summary for NTS

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]

UniProt Comments for NTS

Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Research Articles on NTS

1. Higher concentrations of proneurotensin are associated with a greater risk of incident cardiovascular events in the community. This association did not vary according to sex, baseline low-density lipoprotein, or sortilin receptor 1 genotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NTS recombinant protein

Reference Product	PubMed Publications
FOS recombinant protein	>563 publications with NTS and FOS
CCK recombinant protein	>131 publications with NTS and CCK
NPS recombinant protein	>61 publications with NTS and NPS
NTSR1 recombinant protein	>39 publications with NTS and NTSR1
NTSR2 recombinant protein	>15 publications with NTS and NTSR2
GRP recombinant protein	>5 publications with NTS and GRP
TAC1 recombinant protein	>4 publications with NTS and TAC1
NMU recombinant protein	>2 publications with NTS and NMU

Pathways associated with NTS recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with NTS recombinant protein

Disease Name	Pubmed Publications
Hypertension Antibodies	>399 publications with NTS and Hypertension
Nervous System Diseases Antibodies	>334 publications with NTS and Nervous System Diseases
Bradycardia Antibodies	>278 publications with NTS and Bradycardia
Inflammation Antibodies	>244 publications with NTS and Inflammation
Disease Models, Animal Antibodies	>233 publications with NTS and Disease Models, Animal
Brain Diseases Antibodies	>199 publications with NTS and Brain Diseases
Heart Diseases Antibodies	>141 publications with NTS and Heart Diseases
Pain Antibodies	>135 publications with NTS and Pain
Kidney Diseases Antibodies	>126 publications with NTS and Kidney Diseases
Arrhythmias, Cardiac Antibodies	>84 publications with NTS and Arrhythmias, Cardiac

Organs/Tissues associated with NTS recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3402 publications with NTS and Brain
Heart Antibodies	>875 publications with NTS and Heart
Kidney Antibodies	>232 publications with NTS and Kidney
Stomach Antibodies	>154 publications with NTS and Stomach
Intestine Antibodies	>91 publications with NTS and Intestine
Skin Antibodies	>62 publications with NTS and Skin
Mouth Antibodies	>52 publications with NTS and Mouth
Connective Tissue Antibodies	>36 publications with NTS and Connective Tissue
Pancreas Antibodies	>26 publications with NTS and Pancreas
Embryonic Tissue Antibodies	>23 publications with NTS and Embryonic Tissue