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CDK2AP2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205487

CDK2AP2, also known as DOC-1R and p14, belongs to the CDK2AP family. CDK2-associated protein is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is a regulator for self-renewal of mouse… More details

$230 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDK2AP2, Recombinant Protein
Full Product Name
CDK2AP2, 1-126aa, Human, His tag, E Coli
Product Synonym Names
cyclin-dependent kinase 2 associated protein 2; DOC-1R; p14
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSYKPIA PAPSSTPGSS TPGPGTPVPT GSVPSPSGSV PGAGAPFRPL FNDFGPPSMG YVQAMKPPGA QGSQSTYTDL LSVIEEMGKE IRPTYAGSKS AMERLKRGII HARALVRECL AETERNART
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Purity/Purification
> 95% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
15.5kDa (149aa), confirmed by MALDI-TOF
3D Structure
ModBase 3D Structure for O75956
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for CDK2AP2 recombinant protein

Applications Tested/Suitable for CDK2AP2 recombinant protein
SDS-PAGE

Product References and Citations for CDK2AP2 recombinant protein

Deshpande AM, et al. (2012) Stem Cells Dev. Jun 25.; Shintani, et al. (2000) Mol. Cell. Biol. (uNITED STATES) 20 (17): 6300-7.;

Other Notes

Small volumes of CDK2AP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK2AP2 purchase

MBS205487 is a recombinant protein targeting CDK2AP2. Also known as CDK2AP2, 1-126aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK2AP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase 2-associated protein 2 isoform 1
NCBI Official Synonym Full Names
cyclin dependent kinase 2 associated protein 2
NCBI Official Symbol
CDK2AP2
NCBI Official Synonym Symbols
p14; DOC-1R
UniProt Protein Name
Cyclin-dependent kinase 2-associated protein 2
UniProt Synonym Protein Names
DOC-1-related protein; DOC-1R
UniProt Gene Name
CDK2AP2
UniProt Synonym Gene Names
DOC1R; CDK2-associated protein 2; DOC-1R
NCBI Protein Information
cyclin-dependent kinase 2-associated protein 2

NCBI Summary for CDK2AP2

This gene encodes a protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

UniProt Comments for CDK2AP2

Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDK2AP2 recombinant protein

 Reference Product  PubMed Publications
 CDK2 recombinant protein  >2 publications with CDK2AP2 and CDK2
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