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Integrin Alpha E (ITGaE) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2055179
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MBS2055179 is an antibody targeting ITGaE. Also known as FITC-Linked Polyclonal Antibody to Integrin Alpha E (ITGaE). Reactive in Mouse, Rat. Host: Rabbit. More details

$265 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin Alpha E (ITGaE), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Integrin Alpha E (ITGaE)
Product Gene Name
Product Synonym Names
CD103; ITG-AE; ITGA-E; Mucosal Lymphocyte Antigen 1; HML-1 antigen; Integrin alpha-IEL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Liquid; Supplied as solution form in PBS , pH 8, 1% BSA ,50% glycerol; 0.05% Proclin-300.
Purity/Purification
Antigen-specific Affinity Chromatography
Concentration
0.31mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Keep in dark place
Store at 4 degree C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: ITGaE (MBS2017133)
FITC Conjugated Antibody: ITGaE (MBS2055179)
Matching Pairs
FITC Conjugated Antibody: ITGaE (MBS2055179)
Immunogen: ITGaE (MBS2018223)
OMIM
L25851 mRNA
3D Structure
ModBase 3D Structure for P38570
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Antibody labeling
Label
FITC
Original Antibody
Immunogen
Recombinant ITGaE (Val671~Gln917) expressed in E.coli.
Note
As fluorescence can photobleach when exposed to light, so the antibody must be protected from light
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-ITGaE antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ITGaE antibody
Western blotting: 0.5-2 ug/mL
Immunohistochemistry: 5-20 ug/mL
Immunocytochemistry: 5-20 ug/mL

Optimal working dilutions must be determined by end user.

Other Notes

Small volumes of anti-ITGaE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGaE. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-E
NCBI Official Synonym Full Names
integrin subunit alpha E
NCBI Official Symbol
ITGAE
NCBI Official Synonym Symbols
CD103; HUMINAE
UniProt Protein Name
Integrin alpha-E
UniProt Synonym Protein Names
HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD_antigen: CD103
Protein Family
UniProt Gene Name
ITGAE
NCBI Protein Information
integrin alpha-E

NCBI Summary for ITGaE

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
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UniProt Comments for ITGaE

ITGAE: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Belongs to the integrin alpha chain family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: plasma membrane

Biological Process: extracellular matrix organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ITGaE antibody

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