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SAMSN1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205567

SAMSN1, also known as HACS1, is a member of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. This protein is up-regulated by IL-4 in activated B cells and strongly expressed in dendritic cells. It may have a… More details

$245 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAMSN1, Recombinant Protein
Full Product Name
SAMSN1, 1-373aa, Human, His tag, E Coli
Product Synonym Names
SAM domain-containing protein SAMSN-1; HACS1; NASH1; SASH2; SH3D6B; SLy2
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMLKRKPS NVSEKEKHQK PKRSSSFGNF DRFRNNSLSK PDDSTEAHEG DPTNGSGEQS KTSNNGGGLG KKMRAISWTM KKKVGKKYIK ALSEEKDEED GENAHPYRNS DPVIGTHTEK VSLKASDSMD SLYSGQSSSS GITSCSDGTS NRDSFRLDDD GPYSGPFCGR ARVHTDFTPS PYDTDSLKIK KGDIIDIICK TPMGMWTGML NNKVGNFKFI YVDVISEEEA APKKIKANRR SNSKKSKTLQ EFLERIHLQE YTSTLLLNGY ETLEDLKDIK ESHLIELNIE NPDDRRRLLS AAENFLEEEI IQEQENEPEP LSLSSDISLN KSQLDDCPRD SGCYISSGNS DNGKEDLESE NLSDMVHKII ITEPSD
Host
E Coli
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 30% glycerol 0.1M NaCl, 1mM DTT
Purity/Purification
> 80% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
44.1 kDa (396aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
OMIM
AF222927 mRNA
3D Structure
ModBase 3D Structure for Q9NSI8
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for SAMSN1 recombinant protein

Applications Tested/Suitable for SAMSN1 recombinant protein
SDS-PAGE

Product References and Citations for SAMSN1 recombinant protein

Zhu YX. et al. (2004) J Exp Med. 200:737-747; Wang D. et al. (2010) FASEB J. 24:947-956.

Other Notes

Small volumes of SAMSN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAMSN1 purchase

MBS205567 is a recombinant protein targeting SAMSN1. Also known as SAMSN1, 1-373aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SAMSN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
GenBank Nucleotide #
NCBI Official Full Name
SAM domain-containing protein SAMSN-1 isoform 1
UniProt Protein Name
SAM domain-containing protein SAMSN-1
UniProt Synonym Protein Names
Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; SAM domain, SH3 domain and nuclear localization signals protein 1; SH3-SAM adaptor protein
UniProt Gene Name
SAMSN1
UniProt Synonym Gene Names
HACS1

UniProt Comments for SAMSN1

Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SAMSN1 recombinant protein

 Reference Product  PubMed Publications
 STAT6 recombinant protein  >1 publications with SAMSN1 and STAT6
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