Rabbit Anti-10/1/2017 Polyclonal Antibody – Cat# MBS2056468

Octamer Binding Transcription Factor 1 (OCT1) (10/1/2017) Antibody – Rabbit Polyclonal

Name: 10/1/2017 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2056468
Price: 330 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2056468

MBS2056468 is an antibody targeting 10/1/2017. Also known as APC-Linked Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1). Reactive in Human, Mouse. Host: Rabbit. More details

$330 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Octamer Binding Transcription Factor 1 (OCT1) (10/1/2017), Polyclonal Antibody

Full Product Name

APC-Linked Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1)

Product Gene Name

anti-10/1/2017 antibody

Product Synonym Names

POU2F1; OTF1; NF-A1; POU Domain, Class 2, Transcription Factor 1; Octamer-binding transcription factor 1

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse

Concentration

>=100ug/ml (lot specific)

Matching Pairs

Unconjugated Antibody: OCT1 (MBS2027336)
APC Conjugated Antibody: 10/1/2017 (MBS2056468)

Molecular Weight

33,491 Da

OMIM

L20433 mRNA

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Immunogen

42644 (Ala128~Leu391)

Conjugation

APC

Cross Reactivity

Human, Mouse

Unconjugated Antibody

The unconjugated antibody version of this item is also available as catalog #MBS2027336

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-10/1/2017 antibody

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-10/1/2017 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for 10/1/2017. It may not necessarily be applicable to this product.

NCBI GI #

418016

NCBI GeneID

5457

NCBI Accession #

AAA65605.1

UniProt Secondary Accession #

Q14986; Q15318; Q5T227

UniProt Related Accession #

Q01851

NCBI Official Full Name

octamer binding transcription factor 1

NCBI Official Synonym Full Names

POU class 4 homeobox 1

NCBI Official Symbol

POU4F1

NCBI Official Synonym Symbols

BRN3A; RDC-1; Oct-T1; brn-3A

UniProt Protein Name

POU domain, class 4, transcription factor 1

UniProt Synonym Protein Names

Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1

UniProt Gene Name

POU4F1

UniProt Synonym Gene Names

Brain-3A; Brn-3A

NCBI Protein Information

POU domain, class 4, transcription factor 1

NCBI Summary for 10/1/2017

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012]

UniProt Comments for 10/1/2017

POU4F1: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: nucleoplasm

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; single-stranded DNA binding

Biological Process: axonogenesis; negative regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; neurite development; neuron fate specification; peripheral nervous system neuron development; positive regulation of transcription from RNA polymerase II promoter; sensory system development; synaptogenesis; trigeminal nerve development

Research Articles on 10/1/2017

1. Brn3a cooperates with activated RAS/RAF signalling by reducing oncogene-induced senescence in melanocytic tumourigenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-10/1/2017 antibody

Products by Pathway	Pathway Diagram
Direct P53 Effectors Pathway antibodies	Direct P53 Effectors Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
Regulation Of TP53 Activity Pathway antibodies	Regulation Of TP53 Activity Pathway Diagram
Regulation Of TP53 Activity Through Association With Co-factors Pathway antibodies	Regulation Of TP53 Activity Through Association With Co-factors Pathway Diagram
Transcriptional Regulation By TP53 Pathway antibodies	Transcriptional Regulation By TP53 Pathway Diagram

Diseases associated with anti-10/1/2017 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>22 publications with 10/1/2017 and Nervous System Diseases
Brain Diseases Antibodies	>7 publications with 10/1/2017 and Brain Diseases
Uterine Cervical Neoplasms Antibodies	>7 publications with 10/1/2017 and Uterine Cervical Neoplasms
Nerve Degeneration Antibodies	>4 publications with 10/1/2017 and Nerve Degeneration
Cervical Intraepithelial Neoplasia Antibodies	>4 publications with 10/1/2017 and Cervical Intraepithelial Neoplasia
Vascular Diseases Antibodies	>3 publications with 10/1/2017 and Vascular Diseases
Immune System Diseases Antibodies	>3 publications with 10/1/2017 and Immune System Diseases
Cell Transformation, Neoplastic Antibodies	>3 publications with 10/1/2017 and Cell Transformation, Neoplastic
Leukemia, Myeloid, Acute Antibodies	>3 publications with 10/1/2017 and Leukemia, Myeloid, Acute
Lung Neoplasms Antibodies	>2 publications with 10/1/2017 and Lung Neoplasms

Organs/Tissues associated with anti-10/1/2017 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>46 publications with 10/1/2017 and Brain
Eye Antibodies	>44 publications with 10/1/2017 and Eye
Embryonic Tissue Antibodies	>19 publications with 10/1/2017 and Embryonic Tissue
Blood Antibodies	>5 publications with 10/1/2017 and Blood
Lung Antibodies	>3 publications with 10/1/2017 and Lung
Testis Antibodies	>2 publications with 10/1/2017 and Testis