SSX2 Recombinant Protein

Name: SSX2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205690
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205690

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients,… More details

$230 / 0.004 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSX2, Recombinant Protein

Full Product Name

SSX2, 1-188aa, Human, His tag, E Coli (Denatured)

Product Gene Name

SSX2 recombinant protein

Product Synonym Names

Synovial sarcoma X breakpoint 2B; Synovial sarcoma; X breakpoint 2B; Cancer/testis antigen family 5; member 2b; CT5.2b

Sequence

MGSSHHHHHH SSGLVPRGSH RSMNGDDAFA RRPTVGAQIP EKIQKAFDDI AKYFSKEEWE KMKASEKIFY VYMKRKYEAM TKLGFKATLP PFMCNKRAED FQGNDLDNDP NRGNQVERPQ MTFGRLQGIS PKIMPKKPAE EGNDSEEVPE ASGPQNDGKE LCPPGKPTTS EKIHERSGPK RGEHAWTHRL RERKQLVIYE EISDPEEDDE

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.25 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

24.0 kDa (210 aa)

OMIM

X86175 mRNA

3D Structure

ModBase 3D Structure for Q16385

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for SSX2 recombinant protein

Epigenomics (Transcription & Translation)

Applications Tested/Suitable for SSX2 recombinant protein

SDS-PAGE

Application Notes for SSX2 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for SSX2 recombinant protein

Neumann F, et al. (2013) Cancer Immunol Immunother, PMID 23619976.

Other Notes

Small volumes of SSX2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSX2 purchase

MBS205690 is a recombinant protein targeting SSX2. Also known as SSX2, 1-188aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SSX2. It may not necessarily be applicable to this product.

NCBI GI #

256542319

NCBI GeneID

727837

NCBI Accession #

NP_001157889

UniProt Primary Accession #

Q16385

UniProt Secondary Accession #

Q16404; Q5JS26; Q96IP7; Q9BU88

UniProt Related Accession #

Q16385

GenBank Nucleotide #

NM_001164417.2

NCBI Official Full Name

protein SSX2 isoform b

NCBI Official Synonym Full Names

SSX family member 2B

NCBI Official Symbol

SSX2B

NCBI Official Synonym Symbols

SSX; CT5.2; CT5.2b; HOM-MEL-40

UniProt Protein Name

Protein SSX2

UniProt Synonym Protein Names

Cancer/testis antigen 5.2; CT5.2; Synovial sarcoma, X breakpoint 2; Tumor antigen HOM-MEL-40

Protein Family

Protein

UniProt Gene Name

SSX2

UniProt Synonym Gene Names

SSX2A; CT5.2

NCBI Protein Information

protein SSX2

NCBI Summary for SSX2

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013]

UniProt Comments for SSX2

Could act as a modulator of transcription.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SSX2 recombinant protein

Products by Pathway	Pathway Diagram
Transcriptional Misregulation In Cancer Pathway antibodies	Transcriptional Misregulation In Cancer Pathway Diagram
Transcriptional Misregulation In Cancer Pathway antibodies	Transcriptional Misregulation In Cancer Pathway Diagram