3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

CYB5R2 Recombinant Protein

Name: CYB5R2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205694
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205694

Cytochrome b5 reductase 2, also known as CYB5R2, is involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. This protein is responsible for NADH-dependent lucigenin… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CYB5R2, Recombinant Protein

Full Product Name

CYB5R2, 1-276aa, Human, His tag, E Coli

Product Gene Name

CYB5R2 recombinant protein

Product Synonym Names

Cytochrome b5 reductase 2; B5R.2

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMNSRRRE PITLQDPEAK YPLPLIEKEK ISHNTRRFRF GLPSPDHVLG LPVGNYVQLL AKIDNELVVR AYTPVSSDDD RGFVDLIIKI YFKNVHPQYP EGGKMTQYLE NMKIGETIFF RGPRGRLFYH GPGNLGIRPD QTSEPKKTLA DHLGMIAGGT GITPMLQLIR HITKDPSDRT RMSLIFANQT EEDILVRKEL EEIARTHPDQ FNLWYTLDRP PIGWKYSSGF VTADMIKEHL PPPAKSTLIL VCGPPPLIQT AAHPNLEKLG YTQDMIFTY

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Purity/Purification

> 90% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Molecular Weight

33.8 kDa (299aa) confirmed by MALDI-TOF

OMIM

AF169802 mRNA

3D Structure

ModBase 3D Structure for Q6BCY4

Tag Information

His-tag

Domain

1-276aa

Product Categories/Family for CYB5R2 recombinant protein

Cardiovascular

Applications Tested/Suitable for CYB5R2 recombinant protein

SDS-PAGE

Product References and Citations for CYB5R2 recombinant protein

Baker M.A., et al. (2005) Biol. Reprod. 73:334-342; Zhu H., et al. (1999) Proc. Natl. Acad. Sci. u.S.A. 96:14742-14747;

Other Notes

Small volumes of CYB5R2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYB5R2 purchase

MBS205694 is a recombinant protein targeting CYB5R2. Also known as CYB5R2, 1-276aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CYB5R2. It may not necessarily be applicable to this product.

NCBI GI #

47778923

NCBI GeneID

51700

NCBI Accession #

NP_057313

UniProt Primary Accession #

Q6BCY4

UniProt Secondary Accession #

Q9BVA3; Q9UF68; Q9UHJ0

UniProt Related Accession #

Q6BCY4

GenBank Nucleotide #

NM_016229.4

NCBI Official Full Name

NADH-cytochrome b5 reductase 2 isoform 1

NCBI Official Synonym Full Names

cytochrome b5 reductase 2

NCBI Official Symbol

CYB5R2

NCBI Official Synonym Symbols

B5R.2

UniProt Protein Name

NADH-cytochrome b5 reductase 2

Protein Family

NADH-cytochrome b5 reductase

UniProt Gene Name

CYB5R2

UniProt Synonym Gene Names

b5R.2

NCBI Protein Information

NADH-cytochrome b5 reductase 2

NCBI Summary for CYB5R2

The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

UniProt Comments for CYB5R2

NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).

Research Articles on CYB5R2

1. Study showed that multifocal or multicentric glioblastomas have some underlying genetic and epigenetic characteristics that are associated with poor prognosis and that CYB5R2 is a new epigenetic marker for glioblastoma prognosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CYB5R2 recombinant protein

Reference Product	PubMed Publications
CYB5A recombinant protein	>1 publications with CYB5R2 and CYB5A

Pathways associated with CYB5R2 recombinant protein

Products by Pathway	Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway antibodies	Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
O2/CO2 Exchange In Erythrocytes Pathway antibodies	O2/CO2 Exchange In Erythrocytes Pathway Diagram
Oxidation By Cytochrome P450 Pathway antibodies	Oxidation By Cytochrome P450 Pathway Diagram

Diseases associated with CYB5R2 recombinant protein

Disease Name	Pubmed Publications
Hyperglycemia Antibodies	>1 publications with CYB5R2 and Hyperglycemia
Brain Diseases Antibodies	>1 publications with CYB5R2 and Brain Diseases
Insulin Resistance Antibodies	>1 publications with CYB5R2 and Insulin Resistance
Abnormalities, Drug-Induced Antibodies	>1 publications with CYB5R2 and Abnormalities, Drug-Induced

Organs/Tissues associated with CYB5R2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lymph Node Antibodies	>2 publications with CYB5R2 and Lymph Node
Liver Antibodies	>2 publications with CYB5R2 and Liver
Brain Antibodies	>2 publications with CYB5R2 and Brain
Prostate Antibodies	>1 publications with CYB5R2 and Prostate