GDI2 Recombinant Protein

Name: GDI2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205730
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205730

Rab GDP dissociation inhibitor beta isoform 1, also known as GDI2, belongs to the GDP dissociation inhibitors (GDIs) family. GDIs can bind and release GDP-bound Rab proteins from membranes. Two GDI proteins towards different Rab proteins have been identified.… More details

$230 / 0.004 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GDI2, Recombinant Protein

Full Product Name

GDI2, 1-445aa, Human, His tag, E Coli

Product Gene Name

GDI2 recombinant protein

Product Synonym Names

Rab GDP dissociation inhibitor beta isoform 1; Rab GDP dissociation inhibitor beta isoform 1; RABGDIB

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMNEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESASIT PLEDLYKRFK IPGSPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVTEG SFVYKGGKIY KVPSTEAEAL ASSLMGLFEK RRFRKFLVYV ANFDEKDPRT FEGIDPKKTT MRDVYKKFDL GQDVIDFTGH ALALYRTDDY LDQPCYETIN RIKLYSESLA RYGKSPYLYP LYGLGELPQG FARLSAIYGG TYMLNKPIEE IIVQNGKVIG VKSEGEIARC KQLICDPSYV KDRVEKVGQV IRVICILSHP IKNTNDANSC QIIIPQNQVN RKSDIYVCMI SFAHNVAAQG KYIAIVSTTV ETKEPEKEIR PALELLEPIE QKFVSISDLL VPKDLGTESQ IFISRTYDAT THFETTCDDI KNIYKRMTGS EFDFEEMKRK KNDIYGED

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

53.1 kDa (468aa)

OMIM

D13988 mRNA

3D Structure

ModBase 3D Structure for P50395

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for GDI2 recombinant protein

Signal Transduction

Applications Tested/Suitable for GDI2 recombinant protein

SDS-PAGE

Product References and Citations for GDI2 recombinant protein

Nishimura N., et al. (1995) Cancer Res. 55: 5445-5450.; Sedlacek Z., et al. (1999) Mol Biol Evol. 16: 1231-1237.;

Other Notes

Small volumes of GDI2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDI2 purchase

MBS205730 is a recombinant protein targeting GDI2. Also known as GDI2, 1-445aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GDI2. It may not necessarily be applicable to this product.

NCBI GI #

6598323

NCBI GeneID

2665

NCBI Accession #

NP_001485

UniProt Primary Accession #

P50395

UniProt Secondary Accession #

O43928; Q5SX88; Q9UQM6

UniProt Related Accession #

P50395

GenBank Nucleotide #

NM_001494.3

NCBI Official Full Name

rab GDP dissociation inhibitor beta isoform 1

NCBI Official Synonym Full Names

GDP dissociation inhibitor 2

NCBI Official Symbol

GDI2

NCBI Official Synonym Symbols

RABGDIB; HEL-S-46e

UniProt Protein Name

Rab GDP dissociation inhibitor beta

UniProt Synonym Protein Names

Guanosine diphosphate dissociation inhibitor 2; GDI-2

Protein Family

Guanosine nucleotide diphosphate dissociation inhibitor

UniProt Gene Name

GDI2

UniProt Synonym Gene Names

RABGDIB; Rab GDI beta; GDI-2

NCBI Protein Information

rab GDP dissociation inhibitor beta

NCBI Summary for GDI2

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for GDI2

Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.

Research Articles on GDI2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GDI2 recombinant protein

Reference Product	PubMed Publications
ARHGDIB recombinant protein	>1 publications with GDI2 and ARHGDIB
RHOA recombinant protein	>1 publications with GDI2 and RHOA

Pathways associated with GDI2 recombinant protein

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
RAB GEFs Exchange GTP For GDP On RABs Pathway antibodies	RAB GEFs Exchange GTP For GDP On RABs Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram

Diseases associated with GDI2 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>3 publications with GDI2 and Carcinoma
Neoplasm Metastasis Antibodies	>3 publications with GDI2 and Neoplasm Metastasis
Cell Transformation, Neoplastic Antibodies	>2 publications with GDI2 and Cell Transformation, Neoplastic
Inflammation Antibodies	>2 publications with GDI2 and Inflammation
Urinary Bladder Neoplasms Antibodies	>1 publications with GDI2 and Urinary Bladder Neoplasms
Immune System Diseases Antibodies	>1 publications with GDI2 and Immune System Diseases
Lung Diseases Antibodies	>1 publications with GDI2 and Lung Diseases
Infertility, Male Antibodies	>1 publications with GDI2 and Infertility, Male
Lung Neoplasms Antibodies	>1 publications with GDI2 and Lung Neoplasms
Esophageal Squamous Cell Carcinoma Antibodies	>1 publications with GDI2 and Esophageal Squamous Cell Carcinoma

Organs/Tissues associated with GDI2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with GDI2 and Blood
Lung Antibodies	>3 publications with GDI2 and Lung
Muscle Antibodies	>2 publications with GDI2 and Muscle
Connective Tissue Antibodies	>2 publications with GDI2 and Connective Tissue
Adipose Tissue Antibodies	>2 publications with GDI2 and Adipose Tissue
Bone Antibodies	>2 publications with GDI2 and Bone
Brain Antibodies	>2 publications with GDI2 and Brain
Pancreas Antibodies	>1 publications with GDI2 and Pancreas
Stomach Antibodies	>1 publications with GDI2 and Stomach
Skin Antibodies	>1 publications with GDI2 and Skin