PSG1 Recombinant Protein

Name: PSG1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205767
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205767

PSG1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. PSGs are part of the carcinoembryonic antigen (CEA) family and serve as early biochemical markers of syncytiotrophoblast formation. The sequence… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PSG1, Recombinant Protein

Full Product Name

PSG1, 35-419aa, Human, His tag, E Coli (Denatured)

Product Gene Name

PSG1 recombinant protein

Product Synonym Names

Pregnancy-specific beta-1-glycoprotein 1 isoform 1; Pregnancy-specific beta-1-glycoprotein 1 isoform 1; B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG95; PSGGA; PSGIIA; SP1

Sequence

MGSSHHHHHH SSGLVPRGSH MGSQVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Purity/Purification

> 80% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

45.9kDa (408aa)

OMIM

M20881 mRNA

3D Structure

ModBase 3D Structure for P11464

Antigen Species

Human

Tag Information

His-tag

Applications Tested/Suitable for PSG1 recombinant protein

SDS-PAGE

Application Notes for PSG1 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for PSG1 recombinant protein

Liu H., et al. (2002) Mol Cell Biol. 22: 6471-6479.; Van der Watt P J., et al. (2011) Biochim Biophys Acta. 1809: 316-326.;

Other Notes

Small volumes of PSG1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSG1 purchase

MBS205767 is a recombinant protein targeting PSG1. Also known as PSG1, 35-419aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PSG1. It may not necessarily be applicable to this product.

NCBI GI #

21361392

NCBI GeneID

5669

NCBI Accession #

NP_008836

UniProt Primary Accession #

P11464

UniProt Secondary Accession #

O75236; P11462; P11463; Q15231; Q15241; Q15243; Q16660; Q6ICR4; Q9P1W5; Q9UQ79

UniProt Related Accession #

P11464

GenBank Nucleotide #

NM_006905.2

NCBI Official Full Name

pregnancy-specific beta-1-glycoprotein 1 isoform 1

NCBI Official Synonym Full Names

pregnancy specific beta-1-glycoprotein 1

NCBI Official Symbol

PSG1

NCBI Official Synonym Symbols

SP1; B1G1; PBG1; CD66f; PSBG1; PSG95; PSGGA; DHFRP2; PSBG-1; PSGIIA; FL-NCA-1/2; PS-beta-C/D; PS-beta-G-1

UniProt Protein Name

Pregnancy-specific beta-1-glycoprotein 1

UniProt Synonym Protein Names

CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD_antigen: CD66f

Protein Family

Pregnancy-specific beta-1-glycoprotein

UniProt Gene Name

PSG1

UniProt Synonym Gene Names

B1G1; PSBG1; PSGGA; PS-beta-G-1; PSBG-1; Pregnancy-specific glycoprotein 1; FL-NCA-1/2; PS-beta-C/D

NCBI Protein Information

pregnancy-specific beta-1-glycoprotein 1

NCBI Summary for PSG1

The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]

Research Articles on PSG1

1. Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PSG1 recombinant protein

Reference Product	PubMed Publications
PSG3 recombinant protein	>10 publications with PSG1 and PSG3
PSG6 recombinant protein	>6 publications with PSG1 and PSG6
PSG4 recombinant protein	>6 publications with PSG1 and PSG4
PSG9 recombinant protein	>3 publications with PSG1 and PSG9

Pathways associated with PSG1 recombinant protein

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram

Diseases associated with PSG1 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>8 publications with PSG1 and Nervous System Diseases
Neuromuscular Diseases Antibodies	>1 publications with PSG1 and Neuromuscular Diseases
Disease Models, Animal Antibodies	>1 publications with PSG1 and Disease Models, Animal
Breast Neoplasms Antibodies	>1 publications with PSG1 and Breast Neoplasms
Necrosis Antibodies	>1 publications with PSG1 and Necrosis
Inflammation Antibodies	>1 publications with PSG1 and Inflammation

Organs/Tissues associated with PSG1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>19 publications with PSG1 and Placenta
Embryonic Tissue Antibodies	>2 publications with PSG1 and Embryonic Tissue
Vascular Antibodies	>2 publications with PSG1 and Vascular
Skin Antibodies	>2 publications with PSG1 and Skin
Intestine Antibodies	>1 publications with PSG1 and Intestine