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PAFAH2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205792

PAFAH2 also known as platelet-activating factor acetylhydrolase 2, cytoplasmic. PAFAH2 has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. It may share a common physiologic function with the plasma-type enzyme. Recombinant… More details

$245 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAFAH2, Recombinant Protein
Full Product Name
PAFAH2, 1-392aa, Human, His tag, E Coli
Product Synonym Names
Platelet-activating factor acetylhydrolase 2 cytoplasmic; Platelet-activating factor acetylhydrolase 2; cytoplasmic; HSD-PLA2
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMGVNQSV GFPPVTGPHL VGCGDVMEGQ NLQGSFFRLF YPCQKAEETM EQPLWIPRYE YCTGLAEYLQ FNKRCGGLLF NLAVGSCRLP VSWNGPFKTK DSGYPLIIFS HGLGAFRTLY SAFCMELASR GFVVAVPEHR DRSAATTYFC KQAPEENQPT NESLQEEWIP FRRVEEGEKE FHVRNPQVHQ RVSECLRVLK ILQEVTAGQT VFNILPGGLD LMTLKGNIDM SRVAVMGHSF GGATAILALA KETQFRCAVA LDAWMFPLER DFYPKARGPV FFINTEKFQT MESVNLMKKI CAQHEQSRII TVLGSVHRSQ TDFAFVTGNL IGKFFSTETR GSLDPYEGQE VMVRAMLAFL QKHLDLKEDY NQWNNLIEGI GPSLTPGAPH HLSSL
Host
E Coli
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM DTT
Purity/Purification
> 90% by SDS-PAGE
Concentration
1mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
46.4kDa (415aa) confirmed by MALDI-TOF
OMIM
D87845 mRNA
3D Structure
ModBase 3D Structure for Q99487
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for PAFAH2 recombinant protein

Applications Tested/Suitable for PAFAH2 recombinant protein
SDS-PAGE

Product References and Citations for PAFAH2 recombinant protein

Gregory S.G., et al. (2006) Nature 441:315-321.; Hattori K., et al. (1996) J. Biol. Chem. 271:33032-33038.;

Other Notes

Small volumes of PAFAH2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAFAH2 purchase

MBS205792 is a recombinant protein targeting PAFAH2. Also known as PAFAH2, 1-392aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PAFAH2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet-activating factor acetylhydrolase 2, cytoplasmic
NCBI Official Synonym Full Names
platelet activating factor acetylhydrolase 2
NCBI Official Symbol
PAFAH2
NCBI Official Synonym Symbols
HSD-PLA2
UniProt Protein Name
Platelet-activating factor acetylhydrolase 2, cytoplasmic
UniProt Synonym Protein Names
Serine-dependent phospholipase A2
UniProt Gene Name
PAFAH2
UniProt Synonym Gene Names
SD-PLA2Curated; hSD-PLA2
NCBI Protein Information
platelet-activating factor acetylhydrolase 2, cytoplasmic

NCBI Summary for PAFAH2

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]
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UniProt Comments for PAFAH2

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PAFAH2 recombinant protein

 Reference Product  PubMed Publications
 PAFAH1B1 recombinant protein  >1 publications with PAFAH2 and PAFAH1B1
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