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CD58 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205806

CD58 is a member of the immunoglobulin superfamily. This protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane. Alternatively spliced transcript variants have… More details

$230 / 0.02 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD58, Recombinant Protein
Full Product Name
CD58, 29-215aa, Human, His tag, E Coli (Denatured)
Product Gene Name
Product Synonym Names
CD58 molecule; CD58 molecule; ag3; LFA-3; LFA3
Sequence
MGSSHHHHHH SSGLVPRGSH MGSFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR
Host
E Coli
Form/Format
Liquid. In 20mM Phosphate buffer containing 10% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
23.8kDa (210aa)
OMIM
Y00636 mRNA
3D Structure
ModBase 3D Structure for P19256
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for CD58 recombinant protein

Applications Tested/Suitable for CD58 recombinant protein
SDS-PAGE
Application Notes for CD58 recombinant protein
This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for CD58 recombinant protein

Challa-Malladi,M., et al. (2011) Cancer Cell 20 (6), 728-740; Patsopoulos NA, et al. (2011) Ann. Neurol. 70 (6), 897-912;

Other Notes

Small volumes of CD58 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD58 purchase

MBS205806 is a recombinant protein targeting CD58. Also known as CD58, 29-215aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CD58. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lymphocyte function-associated antigen 3 isoform 1
NCBI Official Synonym Full Names
CD58 molecule
NCBI Official Symbol
CD58
NCBI Official Synonym Symbols
ag3; LFA3; LFA-3
UniProt Protein Name
Lymphocyte function-associated antigen 3
UniProt Synonym Protein Names
Surface glycoprotein LFA-3; CD_antigen: CD58
UniProt Gene Name
CD58
UniProt Synonym Gene Names
LFA3; Ag3
NCBI Protein Information
lymphocyte function-associated antigen 3

NCBI Summary for CD58

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
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UniProt Comments for CD58

Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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