MRPL48 Recombinant Protein

Name: MRPL48 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205814
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205814

Mammalian mitochondrial ribosomal proteins help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MRPL48, Recombinant Protein

Full Product Name

MRPL48, 29-212aa, Human, His tag, E Coli (Denatured)

Product Gene Name

MRPL48 recombinant protein

Product Synonym Names

Mitochondrial ribosomal protein L48; CGI-118; HSPC290; L48MT; MRP-L48

Sequence

MGSSHHHHHH SSGLVPRGSH MGSSGEKPIY SVGGILLSIS RPYKTKPTHG IGKYKHLIKA EEPKKKKGKV EVRAINLGTD YEYGVLNIHL TAYDMTLAES YAQYVHNLCN SLSIKVEESY AMPTKTIEVL QLQDQGSKML LDSVLTTHER VVQISGLSAT FAEIFLEIIQ SSLPEGVRLS VKEHTEEDFK GRFKARPELE ELLAKLK

Host

E Coli

Form/Format

Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol

Purity/Purification

> 85% by SDS-PAGE

Concentration

1 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

23.1 kDa (207aa)

OMIM

AF151876 mRNA

3D Structure

ModBase 3D Structure for Q96GC5

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for MRPL48 recombinant protein

Epigenomics (Transcription & Translation)

Applications Tested/Suitable for MRPL48 recombinant protein

SDS-PAGE

Application Notes for MRPL48 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for MRPL48 recombinant protein

Burkard T.R., et al. (2011) BMC Syst. Biol. 5:17-17; Lai C.-H., et al. (2000) Genome Res. 10:703-713

Other Notes

Small volumes of MRPL48 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRPL48 purchase

MBS205814 is a recombinant protein targeting MRPL48. Also known as MRPL48, 29-212aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MRPL48. It may not necessarily be applicable to this product.

NCBI GI #

7706333

NCBI GeneID

51642

NCBI Accession #

NP_057139

UniProt Primary Accession #

Q96GC5

UniProt Secondary Accession #

Q49AK7; Q4U2Q4; Q9P091; Q9Y5J0; B4DN34

UniProt Related Accession #

Q96GC5

GenBank Nucleotide #

NM_016055.5

NCBI Official Full Name

39S ribosomal protein L48, mitochondrial isoform 1

NCBI Official Synonym Full Names

mitochondrial ribosomal protein L48

NCBI Official Symbol

MRPL48

NCBI Official Synonym Symbols

L48MT; CGI-118; HSPC290; MRP-L48

UniProt Protein Name

39S ribosomal protein L48, mitochondrial

UniProt Synonym Protein Names

Mitochondrial large ribosomal subunit protein mL48

Protein Family

39S ribosomal protein

UniProt Gene Name

MRPL48

UniProt Synonym Gene Names

L48mt; MRP-L48

NCBI Protein Information

39S ribosomal protein L48, mitochondrial

NCBI Summary for MRPL48

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]

Research Articles on MRPL48

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MRPL48 recombinant protein

Reference Product	PubMed Publications
MRPL49 recombinant protein	>1 publications with MRPL48 and MRPL49

Pathways associated with MRPL48 recombinant protein

Products by Pathway	Pathway Diagram
Mitochondrial Translation Pathway antibodies	Mitochondrial Translation Pathway Diagram
Mitochondrial Translation Elongation Pathway antibodies	Mitochondrial Translation Elongation Pathway Diagram
Mitochondrial Translation Initiation Pathway antibodies	Mitochondrial Translation Initiation Pathway Diagram
Mitochondrial Translation Termination Pathway antibodies	Mitochondrial Translation Termination Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with MRPL48 recombinant protein

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>2 publications with MRPL48 and Adenocarcinoma
Cardiovascular Diseases Antibodies	>1 publications with MRPL48 and Cardiovascular Diseases
Liver Diseases Antibodies	>1 publications with MRPL48 and Liver Diseases

Organs/Tissues associated with MRPL48 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with MRPL48 and Muscle
Heart Antibodies	>1 publications with MRPL48 and Heart