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Signal Transducer and Activator of Transcription 3 (STAT3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2058527
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MBS2058527 is an antibody targeting STAT3. Also known as APC-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3). Reactive in Human, Mouse, Rat, Bovine. Host: Rabbit. More details

$330 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Signal Transducer And Activator Of Transcription 3 (STAT3), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3)
Product Gene Name
anti-STAT3 antibody
Product Synonym Names
APRF; Acute-Phase Response Factor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine
Concentration
>=100ug/ml (lot specific)
Matching Pairs
APC Conjugated Antibody: STAT3 (MBS2058527)
Immunogen: STAT3 (MBS2033479)
Matching Pairs
Unconjugated Antibody: STAT3 (MBS2085987)
APC Conjugated Antibody: STAT3 (MBS2058527)
Molecular Weight
87,975 Da
3D Structure
ModBase 3D Structure for P61635
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Thr346~Glu552
Conjugation
APC
Cross Reactivity
Human, Mouse, Rat
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2085987
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-STAT3 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-STAT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STAT3. It may not necessarily be applicable to this product.

NCBI GI #
162287361
NCBI GeneID
508541
NCBI Accession #
NP_001012689.2
UniProt Primary Accession #
P61635
UniProt Related Accession #
P61635
GenBank Nucleotide #
NM_001012671.2
NCBI Official Full Name
signal transducer and activator of transcription 3
NCBI Official Symbol
STAT3
UniProt Protein Name
Signal transducer and activator of transcription 3
Protein Family
Signal transducer and activator of transcription
UniProt Gene Name
STAT3
NCBI Protein Information
signal transducer and activator of transcription 3

UniProt Comments for STAT3

STAT3: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Constitutively active in a number of human tumors. Forms homo- or heterodimers that translocate into the nucleus where they regulate transcription. Two alternatively spliced isoforms have been described.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor co-regulator; Transcription factor

Cellular Component: cytoplasm; nucleus; plasma membrane

Molecular Function: chromatin DNA binding; DNA binding; protein dimerization activity; protein kinase binding; transcription factor activity

Biological Process: astrocyte differentiation; eating behavior; eye photoreceptor cell differentiation; glucose homeostasis; leptin-mediated signaling pathway; phosphorylation; positive regulation of Notch signaling pathway; positive regulation of transcription, DNA-dependent; protein import into nucleus; radial glial cell differentiation; regulation of cell cycle; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; sexual reproduction; thermoregulation
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Research Articles on STAT3

1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STAT3 antibody

 Products by Pathway  Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram

Diseases associated with anti-STAT3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2854 publications with STAT3 and Neoplasms
 Inflammation Antibodies  >1097 publications with STAT3 and Inflammation
 Cardiovascular Diseases Antibodies  >612 publications with STAT3 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >602 publications with STAT3 and Disease Models, Animal
 Necrosis Antibodies  >570 publications with STAT3 and Necrosis
 Adenocarcinoma Antibodies  >457 publications with STAT3 and Adenocarcinoma
 Liver Diseases Antibodies  >427 publications with STAT3 and Liver Diseases
 Nervous System Diseases Antibodies  >384 publications with STAT3 and Nervous System Diseases
 Gastrointestinal Diseases Antibodies  >370 publications with STAT3 and Gastrointestinal Diseases
 Neoplasms, Experimental Antibodies  >329 publications with STAT3 and Neoplasms, Experimental

Organs/Tissues associated with anti-STAT3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1893 publications with STAT3 and Blood
 Liver Antibodies  >919 publications with STAT3 and Liver
 Brain Antibodies  >732 publications with STAT3 and Brain
 Muscle Antibodies  >560 publications with STAT3 and Muscle
 Lung Antibodies  >499 publications with STAT3 and Lung
 Skin Antibodies  >330 publications with STAT3 and Skin
 Kidney Antibodies  >249 publications with STAT3 and Kidney
 Intestine Antibodies  >158 publications with STAT3 and Intestine
 Adipose Tissue Antibodies  >149 publications with STAT3 and Adipose Tissue
 Mammary Gland Antibodies  >115 publications with STAT3 and Mammary Gland
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