CYTH1 Recombinant Protein

Name: CYTH1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205871
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205871

CYTH1 also known as Cytohesin1 isofiorm1. CYTH1 promotes guanine-nucleotide exchange on ARF1 and ARF5 also promotes the activation of ARF factors through replacement of GDP with GTP. Recombinant human CYTH1 was expressed in E Coli and purified by using… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CYTH1, Recombinant Protein

Full Product Name

CYTH1, 1-398aa, Human, His tag, E Coli

Product Gene Name

CYTH1 recombinant protein

Product Synonym Names

Cytohesin1 isofiorm1; B2-1; CYTOHESIN-1; D17S811E; PSCD1; SEC7

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMEEDDSY VPSDLTAEER QELENIRRRK QELLADIQRL KDEIAEVANE IENLGSTEER KNMQRNKQVA MGRKKFNMDP KKGIQFLIEN DLLKNTCEDI AQFLYKGEGL NKTAIGDYLG ERDEFNIQVL HAFVELHEFT DLNLVQALRQ FLWSFRLPGE AQKIDRMMEA FAQRYCQCNN GVFQSTDTCY VLSFAIIMLN TSLHNPNVKD KPTVERFIAM NRGINDGGDL PEELLRNLYE SIKNEPFKIP EDDGNDLTHT FFNPDREGWL LKLGGGRVKT WKRRWFILTD NCLYYFEYTT DKEPRGIIPL ENLSIREVED SKKPNCFELY IPDNKDQVIK ACKTEADGRV VEGNHTVYRI SAPTPEEKEE WIKCIKAAIS RDPFYEMLAA RKKKVSSTKR H

Host

E Coli

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol, 1mM DTT

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

48.8 kDa (421aa) confirmed by MALDI-TOF

OMIM

M85169 mRNA

3D Structure

ModBase 3D Structure for Q15438

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for CYTH1 recombinant protein

Signal Transduction

Applications Tested/Suitable for CYTH1 recombinant protein

SDS-PAGE

Product References and Citations for CYTH1 recombinant protein

Ogasawara M., et al. (2000) J. Biol. Chem. 275:3221-3230.; Betz S.F., et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95:7909-7914.

Other Notes

Small volumes of CYTH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYTH1 purchase

MBS205871 is a recombinant protein targeting CYTH1. Also known as CYTH1, 1-398aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CYTH1. It may not necessarily be applicable to this product.

NCBI GI #

4758964

NCBI GeneID

9267

NCBI Accession #

NP_004753

UniProt Primary Accession #

Q15438

UniProt Secondary Accession #

Q9P123; Q9P124; A6NFW7; B7Z1T4

UniProt Related Accession #

Q15438

GenBank Nucleotide #

NM_004762.3

NCBI Official Full Name

cytohesin-1 isoform 1

NCBI Official Synonym Full Names

cytohesin 1

NCBI Official Symbol

CYTH1

NCBI Official Synonym Symbols

B2-1; SEC7; PSCD1; D17S811E; CYTOHESIN-1

UniProt Protein Name

Cytohesin-1

UniProt Synonym Protein Names

PH, SEC7 and coiled-coil domain-containing protein 1; SEC7 homolog B2-1

Protein Family

Cytohesin

UniProt Gene Name

CYTH1

NCBI Protein Information

cytohesin-1

NCBI Summary for CYTH1

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

UniProt Comments for CYTH1

Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization ().

Research Articles on CYTH1

1. CYTH1 is a novel major regulator of adhesion and engraftment in human hematopoietic stem and progenitor cells through mechanisms that, at least in part, involve the activation of integrins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CYTH1 recombinant protein

Reference Product	PubMed Publications
CYTH3 recombinant protein	>1 publications with CYTH1 and CYTH3
CYTH2 recombinant protein	>1 publications with CYTH1 and CYTH2
CYTH4 recombinant protein	>1 publications with CYTH1 and CYTH4
ARF1 recombinant protein	>1 publications with CYTH1 and ARF1

Pathways associated with CYTH1 recombinant protein

Products by Pathway	Pathway Diagram
Class I PI3K Signaling Events Pathway antibodies	Class I PI3K Signaling Events Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway antibodies	Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway Diagram
Intra-Golgi Traffic Pathway antibodies	Intra-Golgi Traffic Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Phospholipase D Signaling Pathway antibodies	Phospholipase D Signaling Pathway Diagram
Phospholipase D Signaling Pathway antibodies	Phospholipase D Signaling Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram

Organs/Tissues associated with CYTH1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with CYTH1 and Blood
Bone Antibodies	>1 publications with CYTH1 and Bone
Placenta Antibodies	>1 publications with CYTH1 and Placenta
Embryonic Tissue Antibodies	>1 publications with CYTH1 and Embryonic Tissue
Connective Tissue Antibodies	>1 publications with CYTH1 and Connective Tissue
Uterus Antibodies	>1 publications with CYTH1 and Uterus
Muscle Antibodies	>1 publications with CYTH1 and Muscle
Bone Marrow Antibodies	>1 publications with CYTH1 and Bone Marrow