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MSTN Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205998

MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine… More details

$230 / 0.004 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MSTN, Recombinant Protein
Full Product Name
MSTN, 267-375aa, Human, His tag, E Coli (Denatured)
Product Gene Name
Product Synonym Names
Growth/differentiation factor 8; Growth/differentiation factor 8; Myostatin; GDF8; MSLHP
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMDFGLD CDEHSTESRC CRYPLTVDFE AFGWDWIIAP KRYKANYCSG ECEFVFLQKY PHTHLVHQAN PRGSAGPCCT PTKMSPINML YFNGKEQIIY GKIPAMVVDR CGCS
Host
E Coli
Form/Format
Liquid, In 20mM Tris-HCl (pH 8.0) containing 10% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles
Molecular Weight
15.1 kDa (134aa)
OMIM
AF019627 mRNA
3D Structure
ModBase 3D Structure for O14793
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for MSTN recombinant protein

Applications Tested/Suitable for MSTN recombinant protein
SDS-PAGE
Application Notes for MSTN recombinant protein
This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for MSTN recombinant protein

Hill J.J., et al. (2003) Mol. Endocrinol. 17:1144-1154

Other Notes

Small volumes of MSTN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSTN purchase

MBS205998 is a recombinant protein targeting MSTN. Also known as MSTN, 267-375aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MSTN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
growth/differentiation factor 8 preproprotein
NCBI Official Synonym Full Names
myostatin
NCBI Official Symbol
MSTN
NCBI Official Synonym Symbols
GDF8; MSLHP
UniProt Protein Name
Growth/differentiation factor 8
UniProt Synonym Protein Names
Myostatin
UniProt Gene Name
MSTN
UniProt Synonym Gene Names
GDF8; GDF-8
NCBI Protein Information
growth/differentiation factor 8

NCBI Summary for MSTN

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
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UniProt Comments for MSTN

Acts specifically as a negative regulator of skeletal muscle growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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