RNMTL1 Recombinant Protein

Name: RNMTL1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS206091
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206091

RNMTL1 also known as RNA methyltransferase-like protein 1 is belong to the RNA methyltransferase TrmH family. This protein is probable RNA methyltransferase and expressed at same level in normal liver and hepatocarcinoma. Recombinant human RNMTL1, fused to… More details

$230 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RNMTL1, Recombinant Protein

Full Product Name

RNMTL1, 1-420aa, Human, His tag, E Coli (Denatured)

Product Gene Name

RNMTL1 recombinant protein

Product Synonym Names

RNA methyltransferase-like protein 1; RNA methyltransferase-like protein 1; HC90

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAALVRP ARFVVRPLLQ VVQAWDLDAR RWVRALRRSP VKVVFPSGEV VEQKRAPGKQ PRKAPSEASA QEQREKQPLE ESASRAPSTW EESGLRYDKA YPGDRRLSSV MTIVKSRPFR EKQGKILLEG RRLISDALKA GAVPKMFFFS RLEYLKELPV DKLKGVSLIK VKFEDIKDWS DLVTPQGIMG IFAKPDHVKM TYPKTQLQHS LPLLLICDNL RDPGNLGTIL RSAAGAGCSK VLLTKGCVDA WEPKVLRAGM GAHFRMPIIN NLEWETVPNY LPPDTRVYVA DNCGLYAQAE MSNKASDHGW VCDQRVMKFH KYEEEEDVET GASQDWLPHV EVQSYDSDWT EAPAAVVIGG ETYGVSLESL QLAESTGGKR LLIPVVPGVD SLNSAMAASI LLFEGKRQLR GRAEDLSRDR SYH

Host

E Coli

Form/Format

Liquid, In 20mM Tris-HCl (pH 8.0) containing 10% glycerol

Purity/Purification

> 85% by SDS-PAGE

Concentration

1mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

49.4kDa (443aa)

OMIM

AK001443 mRNA

3D Structure

ModBase 3D Structure for Q9HC36

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RNMTL1 recombinant protein

Epigenomics (Transcription & Translation)

Applications Tested/Suitable for RNMTL1 recombinant protein

SDS-PAGE

Application Notes for RNMTL1 recombinant protein

This protein is denatured. Denatured protein is most likely not the best option for functional studies. Denatured protein is better suited for Western Blot (WB) or imaging assays. Applications are user determined.

Product References and Citations for RNMTL1 recombinant protein

Xu J.,et al. (2002) Cell Res. 12:177-197

Other Notes

Small volumes of RNMTL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNMTL1 purchase

MBS206091 is a recombinant protein targeting RNMTL1. Also known as RNMTL1, 1-420aa, Human, His tag, E Coli (Denatured). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RNMTL1. It may not necessarily be applicable to this product.

NCBI GI #

8922534

NCBI GeneID

55178

NCBI Accession #

NP_060616

UniProt Primary Accession #

Q9HC36

UniProt Secondary Accession #

Q53GN1; Q86VC3; Q96F76; Q9NVQ5

UniProt Related Accession #

Q9HC36

GenBank Nucleotide #

NM_018146.3

NCBI Official Full Name

rRNA methyltransferase 3, mitochondrial isoform 1

NCBI Official Synonym Full Names

mitochondrial rRNA methyltransferase 3

NCBI Official Symbol

MRM3

NCBI Official Synonym Symbols

RMTL1; RNMTL1

UniProt Protein Name

rRNA methyltransferase 3, mitochondrial

UniProt Synonym Protein Names

16S rRNA (guanosine(1370)-2'-O)-methyltransferase

UniProt Gene Name

MRM3

NCBI Protein Information

rRNA methyltransferase 3, mitochondrial

NCBI Summary for RNMTL1

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

UniProt Comments for RNMTL1

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Research Articles on RNMTL1

1. MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RNMTL1 recombinant protein

Reference Product	PubMed Publications
RNMTL1 recombinant protein	>2 publications with RNMTL1 and RNMTL1
MRM1 recombinant protein	>1 publications with RNMTL1 and MRM1

Pathways associated with RNMTL1 recombinant protein

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RRNA Modification In The Mitochondrion Pathway antibodies	RRNA Modification In The Mitochondrion Pathway Diagram
RRNA Processing Pathway antibodies	RRNA Processing Pathway Diagram
RRNA Processing In The Mitochondrion Pathway antibodies	RRNA Processing In The Mitochondrion Pathway Diagram

Diseases associated with RNMTL1 recombinant protein

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>1 publications with RNMTL1 and Lung Neoplasms
Fibrosis Antibodies	>1 publications with RNMTL1 and Fibrosis

Organs/Tissues associated with RNMTL1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with RNMTL1 and Blood
Lung Antibodies	>1 publications with RNMTL1 and Lung
Liver Antibodies	>1 publications with RNMTL1 and Liver